CSNK2A1 Protein (OPPA01122)

Catalog No: OPPA01122 (Formerly GWB-B86B89)

Size:3UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: CSNK2A1 is supplied in 25mM Tris-HCl, 500mM NaCl, 1mM DTT, 500um PMSF, 50% glycerol, pH 8.5. Physical appearance: Sterile Filtered clear solution.
• Host: E. Coli
• Additional Information: Unit Definition: No protease activity detectable, specific activity > 1.320 U/mg (1U = 1 umol/min at 37C) using the synthetic peptide RRRDDDSDDD.
  Product Introduction: The Casein kinase 2 (EC2.7.11.1) is a serine/threonine-selective protein kinasethat is a tetramer of two alpha subunits and two beta subunits. The alpha subunits have the catalytic kinase domain. Casein kinase 2 has been implicated in cell cyclecontrol, DNA repair, regulation of the circadian rhythmand other cellular processes. Casein kinase 2 activity has been reported to be activated following Wnt signaling pathwayactivation. A Pertussis toxin-sensitive G proteinand Disheveled appear to be an intermediary between Wnt-mediated activation of the Frizzled receptor and activation of casein kinase 2.Mice that lack casein kinase 2 alpha prime have a defect in the morphology of developing sperm.
  Product Description: Casein Kinase 2 alpha Human Recombinant is a non-glycosylated polypeptide having a molecular mass of 45.1 kDa. Casein Kinase 2 is purified by proprietary chromatographic techniques.
• Reconstitution and Storage: Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. Avoid multiple freeze-thaw cycles.
• Purity: Greater than 99% as determined by SDS-PAGE.

Target Info

• Gene Symbol: CSNK2A1
• Alias Symbols: CKII, Cka1, Cka2, CK2A1, OCNDS
• NCBI Gene Id: 1457
• Protein Name: Casein kinase II subunit alpha
• Description of Target: Recombinant Human Casein Kinase 2 alpha
• Uniprot ID: P68400
• Protein Accession #: NP_001886.1
• Protein Size (# AA): Recombinant