CLDN5 Antibody (Phospho-Tyr217) (OASG01621)

Catalog No: OASG01621

Size:100 uL

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human Claudin-5 around the phosphorylation site of Y217. Location: 150-230aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Tyr217
• Specificity: Phospho-Claudin-5 (Tyr217) Polyclonal Antibody detects endogenous levels of Claudin-5 protein only when phosphorylated at Y217.
• Application Info: IHC 1:100-1:300; ELISA 1:5000;

Target Info

• Gene Symbol: CLDN5
• Gene Full Name: claudin 5
• Alias Symbols: AWAL, BEC1, TMVCF, TMDVCF, CPETRL1
• NCBI Gene Id: 7122; 12741; 65131
• Description of Target: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
• Uniprot ID: O00501, O54942, Q9JKD6
• Molecular Weight: 23 kDa