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- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for CHAT antibody OAPC00231 |
|---|
| Predicted Species Reactivity | Human, Mouse, Chicken, Guinea Pig |
|---|---|
| Product Format | 100 ul in in PBS + 5 mg/ml BSA + 0.2% NaN3. |
| Clonality | Polyclonal |
| Host | Goat |
| Application | WB, IHC |
| Reconstitution and Storage | For long term storage -20C is recommended. Stable at -20C for at least 1 year. Avoid freeze/thaw cycles. |
| Immunogen | Native choline acetyltransferase purifed from human placenta |
| Purification | Affinity Purified |
| Specificity | Specific for ~70k ChAT protein. |
| Application Info | WB ~ 1:100 |
| Gene Symbol | CHAT |
|---|---|
| Gene Full Name | choline O-acetyltransferase |
| Alias Symbols | CMS6, CMS1A, CMS1A2, CHOACTASE |
| NCBI Gene Id | 1103 |
| Description of Target | Choline acetyltransferase is a neuronal enzyme which catalyzes the reaction between Acetyl CoA and choline resulting in the formation of acetylcholine. It is therefore found primarily in cholinergic neurons making it a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia, Alzheimer disease (AD) and Down syndrome (Holt et al. 1999). Decreased choline acetyltransferase activity in particular has been shown in Schizophrenic subjects (Karson et al 1993). It has furthermore been demonstrated that in patients with AD, there are significantly lower levels of cortical ChAT that correlate with severity of the disease as measured by loss of neuropsychological function (Baskin et al. 1999). |
| Uniprot ID | P28329. |
| Molecular Weight | 70 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "CHAT Antibody (OAPC00231)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Chicken, Guinea Pig".
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How long will it take to receive "CHAT Antibody (OAPC00231)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "CHAT Antibody (OAPC00231)" provided in?
This item is provided in "100 ul in in PBS + 5 mg/ml BSA + 0.2% NaN3.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CHAT Antibody (OAPC00231)"?
This target may also be called "CMS6, CMS1A, CMS1A2, CHOACTASE" in publications.
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What is the shipping cost for "CHAT Antibody (OAPC00231)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "CHAT Antibody (OAPC00231)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CHAT Antibody (OAPC00231)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "70 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CHAT Antibody (OAPC00231)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CHAT"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CHAT"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CHAT"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CHAT"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CHAT"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CHAT"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
