CEBPA Antibody (Phospho-Thr226) (OASG00865)

Catalog No: OASG00865

Size:100 uL

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Monkey
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human C/EBP Alpha around the phosphorylation site of T226. Location: 170-250aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Thr226
• Specificity: Phospho-C/EBP Alpha (T226) Polyclonal Antibody detects endogenous levels of C/EBP Alpha protein only when phosphorylated at T226.
• Application Info: WB 1:500-1:2000; ELISA 1:10000;

Target Info

• Gene Symbol: CEBPA
• Gene Full Name: CCAAT/enhancer binding protein (C/EBP), alpha
• Alias Symbols: CEBP, C/EBP-alpha
• NCBI Gene Id: 1050; 12606; 24252
• Description of Target: This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.
• Uniprot ID: P49715, P53566, P05554
• Molecular Weight: 37 kDa