Size:100 ul
Special Price $229.00 Regular Price $289.00
In Stock
SKU
ARP57937_P050
Request Bulk
Order Quote
Aviva's
Satisfaction
Guarantee
Contact Us:
  • Toll Free: (888)880-0001
  • Phone: (858)552-6979
  • Email: info@avivasysbio.com
Shipping Info:
  • $40: Antibody & Protein in US
  • $50: 1-2 Kits in US
  • Contact us for international orders.

Conjugation Options

ARP57937_P050-FITC Conjugated

ARP57937_P050-HRP Conjugated

ARP57937_P050-Biotin Conjugated

CEBPA Antibody - middle region (ARP57937_P050)

Catalog#: ARP57937_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB, IHC
Additional Information IHC Information: Prostate
IHC Information: Colon
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-126522 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CEBPA
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 79%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 79%; Zebrafish: 93%
Complete computational species homology data Anti-CEBPA (ARP57937_P050)
Peptide Sequence Synthetic peptide located within the following region: RRERNNIAVRKSRDKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDT
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-CEBPA (ARP57937_P050) antibody is Catalog # AAP57937 (Previous Catalog # AAPP32348)
Datasheets/Manuals Printable datasheet for anti-CEBPA (ARP57937_P050) antibody
Target Reference Singh,S.M., (2008) Biochem. Biophys. Res. Commun. 369 (2), 692-694
Publications

Borger, P. et al. Impaired translation of CCAAT/enhancer binding protein alpha mRNA in bronchial smooth muscle cells of asthmatic patients. J. Allergy Clin. Immunol. 123, 639-45 (2009). WB, IHC, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish 19121862

Miglino, N., Roth, M., Tamm, M. & Borger, P. House dust mite extract downregulates C/EBP-alpha in asthmatic bronchial smooth muscle cells. Eur. Respir. J. 38, 50-8 (2011). WB, IHC, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish 21109558

Gene Symbol CEBPA
Official Gene Full Name CCAAT/enhancer binding protein (C/EBP), alpha
Alias Symbols C/EBP-alpha, CEBP
NCBI Gene Id 1050
Protein Name CCAAT/enhancer-binding protein alpha
Description of Target CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2385 U34070.1 592-2976
Swissprot Id P49715
Protein Accession # NP_004355
Nucleotide Accession # NM_004364
Protein Size (# AA) 358
Molecular Weight 37kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express CEBPA.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express CEBPA.
Protein Interactions CEBPB; ZBTB16; RARA; HDAC1; BHLHE41; UBC; CEBPE; BATF2; BATF3; YY1AP1; ATF5; BATF; FOSL1; FOS; DBP; CEBPG; CEBPA; ATF4; ATF3; UBE3A; SKP2; RASGRF1; C1QBP; CDKN1A; SRA1; CDK4; PIAS1; Fbxw7; GRIN3A; RAB34; NAA16; POLR1E; MRTO4; AK5; MACF1; KAT5; AKAP9; SMC1
  1. What is the species homology for "CEBPA Antibody - middle region (ARP57937_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish".

  2. How long will it take to receive "CEBPA Antibody - middle region (ARP57937_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "CEBPA Antibody - middle region (ARP57937_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CEBPA Antibody - middle region (ARP57937_P050)"?

    This target may also be called "C/EBP-alpha, CEBP" in publications.

  5. What is the shipping cost for "CEBPA Antibody - middle region (ARP57937_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CEBPA Antibody - middle region (ARP57937_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CEBPA Antibody - middle region (ARP57937_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "37kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CEBPA Antibody - middle region (ARP57937_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "CEBPA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CEBPA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CEBPA"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CEBPA"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CEBPA"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CEBPA"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:CEBPA Antibody - middle region (ARP57937_P050)
Your Rating
We found other products you might like!