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| Datasheets/Manuals | Printable datasheet for anti-CD8 antibody - OAPA00149 |
|---|
| Predicted Species Reactivity | Mouse |
|---|---|
| Clonality | Monoclonal |
| Clone | NYRmCD8. |
| Isotype | Rat IgM. |
| Host | Rat |
| Additional Information | Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4C. |
| :: | Product Type: Rat Anti Mouse Monoclonal. |
| :: | Antibody Properties: Cytotoxic and staining antibody. For staining, use 10 ul/10^6 cells. Titer for cytotoxicity should be determined by the investigator. |
| :: | Product Introduction: CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional CD8 is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 identifies cytotoxic/suppressor t-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of t-cell mediated killing. CD8 alpha chains bind to class-I MHC molecules alpha-3 domains. |
| Reconstitution and Storage | Lyophilized: store at 4C. After reconstitution, if not intended for use within a month, aliquot and store at -20C. |
| Immunogen | The immunogen for anti-CD8 antibody: purified Mouse LN T cells. |
| Purity | Ion Exchange Column. |
| Gene Symbol | CD8 |
|---|---|
| Alias Symbols | CD8, p32, Leu2 |
| NCBI Gene Id | 925 |
| Protein Name | T-cell surface glycoprotein CD8 alpha chain |
| Description of Target | Rat Anti Mouse CD8 |
| Uniprot ID | P01732 |
| Protein Accession # | NP_001139345.1 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "CD8 Antibody (OAPA00149)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse".
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How long will it take to receive "CD8 Antibody (OAPA00149)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "CD8 Antibody (OAPA00149)" provided in?
This item is provided in "".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CD8 Antibody (OAPA00149)"?
This target may also be called "CD8, p32, Leu2" in publications.
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What is the shipping cost for "CD8 Antibody (OAPA00149)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "CD8 Antibody (OAPA00149)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CD8 Antibody (OAPA00149)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CD8 Antibody (OAPA00149)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CD8"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CD8"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CD8"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CD8"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CD8"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CD8"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
