CALR Recombinant Protein (OPCD02437)

Catalog No: OPCD02437

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Leu196-Asn310
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: CALR
• Gene Full Name: calreticulin
• Alias Symbols: calregulin;calreticulin;cC1qR;CRP55;CRT;endoplasmic reticulum resident protein 60;epididymis secretory sperm binding protein Li 99n;ERp60;grp60;HACBP;HEL-S-99n;RO;Sicca syndrome antigen A (autoantigen Ro; calreticulin);SSA.
• NCBI Gene Id: 811
• Protein Name: Calreticulin
• Description of Target: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).
• Uniprot ID: P27797
• Protein Accession #: NP_004334.1
• Nucleotide Accession #: NM_004343.3
• Protein Size (# AA): Leu196~Asn310
• Molecular Weight: 17kDa