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BMPR1A Antibody - N-terminal region : FITC (ARP73773_P050-FITC)

100 ul
$289.00
In Stock
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Conjugation Options

ARP73773_P050 Unconjugated

ARP73773_P050-HRP Conjugated

ARP73773_P050-Biotin Conjugated

Gene Symbol:
BMPR1A
NCBI Gene Id:
657
Swissprot Id:
P36894
Protein Accession #:
XP_005270121
Alias Symbols:
BMPR1A, ACVRLK3, ALK3,
Replacement Item:
This antibody may replace item sc-134285 from Santa Cruz Biotechnology.
Description of Target:
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Protein Size (# AA):
532
Molecular Weight:
58kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express BMPR1A.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express BMPR1A.
Immunogen:
The immunogen is a synthetic peptide directed towards the N-terminal region of Human BMPR1A
Predicted Species Reactivity:
Human
Peptide Sequence:
Synthetic peptide located within the following region: GMKSDSDQKKSENGVTLAPEDTLPFLKCYCSGHCPDDAINNTCITNGHCF
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution and Storage:
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Concentration:
0.5 mg/ml
Protein Interactions:
UBC; USP15; BMPR1A; ACVR1; PEG10; CAV1; HSP90AA1; BAMBI; SMAD7; SMAD6; SMAD1; MYC; SMURF1; Nedd4; NEDD4L; FST; IGSF1; TSC22D1; RUNX2; SF3B4; GDF6; ZMYND11; TGFBRAP1; BMPR1B; TAB1; GDF9; GDF5; BMPR2; HOXC8; BMP7; BMP6; BMP5; BMP4; BMP2; FKBP1A; FKBP1B;
Blocking Peptide:
For anti-BMPR1A (ARP73773_P050-FITC) antibody is Catalog # AAP73773
Datasheets/Manuals:
Printable datasheet for anti-BMPR1A (ARP73773_P050-FITC) antibody
Conjugation:
FITC (FAM): Excitation 495 nm/ Emission 520 nm

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