BMPR1A Antibody - N-terminal region : FITC (ARP73773_P050-FITC)

Data Sheet
 
Product Number ARP73773_P050-FITC
Product Page www.avivasysbio.com/bmpr1a-antibody-n-terminal-region-fitc-arp73773-p050-fitc.html
Name BMPR1A Antibody - N-terminal region : FITC (ARP73773_P050-FITC)
Protein Size (# AA) 532 amino acids
Molecular Weight 58kDa
Conjugation FITC: Fluorescein Isothiocyanate
NCBI Gene Id 657
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Alias Symbols ALK3, SKR5, CD292, ACVRLK3, 10q23del
Peptide Sequence Synthetic peptide located within the following region: GMKSDSDQKKSENGVTLAPEDTLPFLKCYCSGHCPDDAINNTCITNGHCF
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Description of Target The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Protein Interactions UBC; USP15; BMPR1A; ACVR1; PEG10; CAV1; HSP90AA1; BAMBI; SMAD7; SMAD6; SMAD1; MYC; SMURF1; Nedd4; NEDD4L; FST; IGSF1; TSC22D1; RUNX2; SF3B4; GDF6; ZMYND11; TGFBRAP1; BMPR1B; TAB1; GDF9; GDF5; BMPR2; HOXC8; BMP7; BMP6; BMP5; BMP4; BMP2; FKBP1A; FKBP1B;
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-BMPR1A (ARP73773_P050-FITC) antibody
Blocking Peptide For anti-BMPR1A (ARP73773_P050-FITC) antibody is Catalog # AAP73773
Immunogen The immunogen is a synthetic peptide directed towards the N-terminal region of Human BMPR1A
Uniprot ID P36894
Protein Accession # XP_005270121
Purification Affinity Purified
Gene Symbol BMPR1A
Predicted Species Reactivity Human
Application WB
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