Product Number |
ARP73773_P050-FITC |
Product Page |
www.avivasysbio.com/bmpr1a-antibody-n-terminal-region-fitc-arp73773-p050-fitc.html |
Name |
BMPR1A Antibody - N-terminal region : FITC (ARP73773_P050-FITC) |
Protein Size (# AA) |
532 amino acids |
Molecular Weight |
58kDa |
Conjugation |
FITC: Fluorescein Isothiocyanate |
NCBI Gene Id |
657 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Alias Symbols |
ALK3, SKR5, CD292, ACVRLK3, 10q23del |
Peptide Sequence |
Synthetic peptide located within the following region: GMKSDSDQKKSENGVTLAPEDTLPFLKCYCSGHCPDDAINNTCITNGHCF |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
Description of Target |
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. |
Protein Interactions |
UBC; USP15; BMPR1A; ACVR1; PEG10; CAV1; HSP90AA1; BAMBI; SMAD7; SMAD6; SMAD1; MYC; SMURF1; Nedd4; NEDD4L; FST; IGSF1; TSC22D1; RUNX2; SF3B4; GDF6; ZMYND11; TGFBRAP1; BMPR1B; TAB1; GDF9; GDF5; BMPR2; HOXC8; BMP7; BMP6; BMP5; BMP4; BMP2; FKBP1A; FKBP1B; |
Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Datasheets/Manuals |
Printable datasheet for anti-BMPR1A (ARP73773_P050-FITC) antibody |
Blocking Peptide |
For anti-BMPR1A (ARP73773_P050-FITC) antibody is Catalog # AAP73773 |
Immunogen |
The immunogen is a synthetic peptide directed towards the N-terminal region of Human BMPR1A |
Uniprot ID |
P36894 |
Protein Accession # |
XP_005270121 |
Purification |
Affinity Purified |
Gene Symbol |
BMPR1A |
Predicted Species Reactivity |
Human |
Application |
WB |
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