Catalog No: OPCD01599
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Datasheets/ManualsPrintable datasheet for OPCD01599
Product Info
Predicted Species ReactivityHuman
Product FormatLyophilized 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% Sarkosyl, 5% Trehalose and Proclin300
ApplicationPositive Control; Immunogen; SDS-PAGE; WB
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
Residues: Met1-Arg210
Subcellular Location: Nucleus, Cytoplasm
Predicted Isoelectric Point: 6.1
::Phenomenon explanation:
The possible reasons that the actual band size differs from the predicted are as follows:
1. Splice variants: Alternative splicing may create different sized proteins from the same gene.
2. Relative charge: The composition of amino acids may affect the charge of the protein.
3. Post-translational modification: Phosphorylation, glycosylation, methylation etc.
4.Post-translationcleavage:Manyproteinsaresynthesizedaspro-proteins,and then cleaved to give the active form.
5. Polymerization of the target protein: Dimerization, multimerization etc.
Reconstitution and StorageReconstitute in ddH2O to the original concentration prior to lyophilization. If additional dilution is required, dilute further in the original base lyophilization buffer excluding stabilizers such as Sarkosyl, Proclin, Trehalose or Sucrose. Do not vortex. Store at 2-8C for one month. Aliquot and store at -80C for 12 months. Avoid repeated freeze/thaw cycles.
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceProkaryotic expression
TagN-terminal His Tag
Gene SymbolBCL11A
Gene Full NameB-cell CLL/lymphoma 11A
Alias SymbolsEVI9, CTIP1, DILOS, ZNF856, HBFQTL5, BCL11A-L, BCL11A-S, BCL11a-M, BCL11A-XL
NCBI Gene Id53335
Protein NameB-cell lymphoma/leukemia 11A
Description of TargetFunctions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1.
Swissprot IdQ9H165
Protein Accession #NP_060484.2
Nucleotide Accession #NM_018014.3
Molecular Weight27 kDa
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express BCL11A.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express BCL11A.
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