BCL11A Recombinant Protein (OPCD01599)

Catalog No: OPCD01599

BCL11A Recombinant Protein (OPCD01599) using SDS-PAGE

BCL11A Recombinant Protein (OPCD01599) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Met1-Arg210
  Subcellular Location: Nucleus, Cytoplasm
  Predicted Isoelectric Point: 6.1
  Phenomenon explanation:
  The possible reasons that the actual band size differs from the predicted are as follows:
  1. Splice variants: Alternative splicing may create different sized proteins from the same gene.
  2. Relative charge: The composition of amino acids may affect the charge of the protein.
  3. Post-translational modification: Phosphorylation, glycosylation, methylation etc.
  4.Post-translationcleavage:Manyproteinsaresynthesizedaspro-proteins,and then cleaved to give the active form.
  5. Polymerization of the target protein: Dimerization, multimerization etc.
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: BCL11A
• Gene Full Name: BAF chromatin remodeling complex subunit BCL11A
• Alias Symbols: B cell CLL/lymphoma 11A;B-cell CLL/lymphoma 11A;B-cell CLL/lymphoma 11A (zinc finger protein);B-cell lymphoma/leukemia 11A;BCL11A B-cell CLL/lymphoma 11A (zinc finger protein);BCL11A, BAF complex component;BCL11A-L;BCL11a-M;BCL11A-S;BCL11A-XL;C2H2-type zinc finger protein;COUP-TF-interacting protein 1;CTIP1;DILOS;ecotropic viral integration site 9 homolog;ecotropic viral integration site 9 protein homolog;EVI9;HBFQTL5;SMARCM1;zinc finger protein 856;ZNF856.
• NCBI Gene Id: 53335
• Protein Name: B-cell lymphoma/leukemia 11A
• Description of Target: Transcription factor associated with the BAF SWI/SNF chromatin remodeling complex (By similarity). Repressor of fetal hemoglobin (HbF) level (PubMed:26375765). Involved in brain development (PubMed:27453576). Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. Essential factor in lymphopoiesis required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1 (By similarity).
• Uniprot ID: Q9H165
• Protein Accession #: NP_060484.2
• Nucleotide Accession #: NM_018014.3
• Protein Size (# AA): Met1~Arg210
• Molecular Weight: 32kDa