| Product Number |
OPCD01599 |
| Product Page |
www.avivasysbio.com/bcl11a-recombinant-protein-opcd01599.html |
| Name |
BCL11A Recombinant Protein (OPCD01599) |
| Protein Size (# AA) |
Met1~Arg210 amino acids |
| Molecular Weight |
32kDa |
| Tag |
N-terminal His Tag |
| Conjugation |
Unconjugated |
| NCBI Gene Id |
53335 |
| Host |
E.coli |
| Purity |
> 95% |
| Concentration |
200 ug/mL (prior to lyoph) |
| Source |
E.coli |
| Gene Full Name |
BAF chromatin remodeling complex subunit BCL11A |
| Alias Symbols |
B cell CLL/lymphoma 11A;B-cell CLL/lymphoma 11A;B-cell CLL/lymphoma 11A (zinc finger protein);B-cell lymphoma/leukemia 11A;BCL11A B-cell CLL/lymphoma 11A (zinc finger protein);BCL11A, BAF complex component;BCL11A-L;BCL11a-M;BCL11A-S;BCL11A-XL;C2H2-type zinc finger protein;COUP-TF-interacting protein 1;CTIP1;DILOS;ecotropic viral integration site 9 homolog;ecotropic viral integration site 9 protein homolog;EVI9;HBFQTL5;SMARCM1;zinc finger protein 856;ZNF856. |
| Product Format |
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
| Description of Target |
Transcription factor associated with the BAF SWI/SNF chromatin remodeling complex (By similarity). Repressor of fetal hemoglobin (HbF) level (PubMed:26375765). Involved in brain development (PubMed:27453576). Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. Essential factor in lymphopoiesis required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1 (By similarity). |
| Reconstitution and Storage |
2°C to 8°C|-80°C |
| Datasheets/Manuals |
Printable datasheet for BCL11A Recombinant Protein (OPCD01599) |
| Additional Information |
Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
Residues: Met1-Arg210
Subcellular Location: Nucleus, Cytoplasm
Predicted Isoelectric Point: 6.1 |
| Additional Information |
Phenomenon explanation:
The possible reasons that the actual band size differs from the predicted are as follows:
1. Splice variants: Alternative splicing may create different sized proteins from the same gene.
2. Relative charge: The composition of amino acids may affect the charge of the protein.
3. Post-translational modification: Phosphorylation, glycosylation, methylation etc.
4.Post-translationcleavage:Manyproteinsaresynthesizedaspro-proteins,and then cleaved to give the active form.
5. Polymerization of the target protein: Dimerization, multimerization etc. |
| Uniprot ID |
Q9H165 |
| Protein Name |
B-cell lymphoma/leukemia 11A |
| Protein Accession # |
NP_060484.2 |
| Nucleotide Accession # |
NM_018014.3 |
| Gene Symbol |
BCL11A |
| Predicted Species Reactivity |
Homo sapiens|Human |
| Application |
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
| Image 1 | SDS-PAGE
 | BCL11A Recombinant Protein (OPCD01599) using SDS-PAGE |
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