ANXA2 Recombinant Protein (OPCD01355)

Catalog No: OPCD01355

ANXA2 Recombinant Protein (OPCD01355) using SDS-PAGE

ANXA2 Recombinant Protein (OPCD01355) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Val46-Glu181
  Subcellular Location: Secreted. extracellular space, extracellular matrix basement membrane. Melanosome.
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Anxa2
• Gene Full Name: annexin A2
• Alias Symbols: 33-kDa calcimedin;33kDa lymphocyte Ca<2+>- binding protein;33-kDa lymphocyte Ca<2+>- binding protein;36-kDa calelectrin;annexin A2;annexin II;annexin-2;AW215814;Cal;Cal1h;calpactin I heavy chain;calpactin-1 heavy chain;chromobindin-8;lipocortin II;p36;PAP-IV;placental anticoagulant protein IV;protein I.
• NCBI Gene Id: 12306
• Protein Name: Annexin A2
• Description of Target: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response (By similarity). Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:22848640).
• Uniprot ID: P07356
• Protein Accession #: NP_031611.1
• Nucleotide Accession #: NM_007585.3
• Protein Size (# AA): Met1~Asp339
• Molecular Weight: 42kDa