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Anti-Meteorin Antibody (NT) Polyclonal Antibody (OAAI00402)

100 ug
$265.00
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Gene Symbol:
METRN
Official Gene Full Name:
meteorin, glial cell differentiation regulator
NCBI Gene Id:
79006
Swissprot Id:
Q9UJH8
Alias Symbols:
C16orf23, c380A1.2,
Replacement Item:
This antibody may replace item sc-149377 from Santa Cruz Biotechnology.
Description of Target:
The Meteorin, a secreted protein, is expressed in undifferentialted neural progenitors and in astrocyte lineage, including radial glia, or glical cells which are major components of the nervous system. Meteorin selectively promoted astrocyte formation from Mouse cerebrocortical neurospheres in differentiation culture, whereas it induced cerebellar astrocytes to become radial glia. Meteorin also induced axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia. Meteorin plays important roles in both glial cell differentiation and axonal network formation during neurogenesis.
Molecular Weight:
~30 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
The Rabbit IgG is purified by specific Epitope Affinity Purification.
Application:
ELISA, IHC, WB, IP
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express METRN.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express METRN.
Immunogen:
A synthetic peptide corresponding to the N-terminus of Meteorin protein. This sequence is identical among Human, Mouse.
Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid TBS (pH 7.2) containing antibody stabilizer
Reconstitution and Storage:
The antibodies are stable for 12 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C to 8C for three month without detectable loss of activity.
Avoid repeated freezing thawing cycles.
Concentration:
0.5 mg/ml
Datasheets/Manuals:
Printable datasheet for Rabbit Anti-Meteorin Antibody (NT) Polyclonal AntibodyOAAI00402
Specificity:
This antibody recognizes ~30 kDa of METRN protein. It cross react with Mouse, Rat and Human. The other species are not tested.
Isotype:
Rabbit IgG
Application Info:
WB: 0.1-1 ug/mL
ELISA: 0.01-0.1 ug/mL
IP: 2-5 ug/mL
IHC: 2-5 ug/mL
:::
Positive Controls: Brain tissue
Cellular Location: Extracellular or cytoplasmic
Target Reference:
Nishino,J., Yamashita,K., Hashiguchi,H., Fujii,H., Shimazaki,T. and Hamada,H. Meteorin: a secreted protein that regulates glial cell differentiation and promotes axonal extension. EMBO J. 23 (9), 1998-2008 (2004)

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