Anti-Meteorin Antibody (CT) Polyclonal Antibody (OAAI00404)

Catalog No: OAAI00404

Size:100UG

Western Blot: The whole cell lysate derived from mouse brain tissue was immnoblotted by Rabbit anti-METRN (CT) (Cat#OAAI00404) at 1:500. An immunoreactive band around 30kDa was observed.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot
• Additional Information: Background: The Meteorin, a secreted protein, is expressed in undifferentialted neural progenitors and in astrocyte lineage, including radial glia, or glical cells which are major components of the nervous system. Meteorin selectively promoted astrocyte formation from mouse cerebrocortical neurospheres in differentiation culture, whereas it induced cerebellar astrocytes to become radial glia. Meteorin also induced axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia. Meteorin plays important roles in both glial cell differentiation and axonal network formation during neurogenesis.
  Positive Control: Brain tissue
  Cellular Location: Extracellular or cytoplasmic
• Reconstitution and Storage: The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
• Immunogen: A synthetic peptide corresponding to the C-terminus of Meteorin protein. This sequence is identical among human, rat and mouse.
• Purification: Affinity Purified
• Concentration: 100ug/200ul
• Specificity: METRN
• Formulation: This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Application Info: WB: 0.1-1 ug/ml | ELISA: 0.01-0.1 ug/ml | IP: 2-5 ug/ml | IHC: 2-10 ug/ml | FC: Not tested
• Reference: Nishino,J., Yamashita,K., Hashiguchi,H., Fujii,H., Shimazaki,T. and Hamada,H. Meteorin: a secreted protein that regulates glial cell differentiation and promotes axonal extension. EMBO J. 23 (9), 1998-2008 (2004)

Target Info

• Gene Symbol: METRN
• Gene Full Name: meteorin, glial cell differentiation regulator
• Alias Symbols: C16orf23;c380A1.2;meteorin.
• NCBI Gene Id: 79006
• Description of Target: The Meteorin, a secreted protein, is expressed in undifferentialted neural progenitors and in astrocyte lineage, including radial glia, or glical cells which are major components of the nervous system. Meteorin selectively promoted astrocyte formation from Mouse cerebrocortical neurospheres in differentiation culture, whereas it induced cerebellar astrocytes to become radial glia. Meteorin also induced axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia. Meteorin plays important roles in both glial cell differentiation and axonal network formation during neurogenesis.
  
• Uniprot ID: Q9UJH8
• Molecular Weight: 30