Anti-FOXP1 Antibody (OAAI00583)

Catalog No: OAAI00583

Size:100UG

Western Blot: The Hela cell lysate was immuno- blotted by Rabbit anti FOXP1 antibody, (Cat#OAAI00583) at 1:500 (Lane 1). Lane 2 was pre- incubated with immunizing peptide.

Rbx FOXP1 staining on Formalin-fixed paraffin-embedded human tonsil (10 ug/ml)

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot
• Additional Information: Background: FOXP1 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
  Positive Control: Hela
  Cellular Location: Nucleus.
• Reconstitution and Storage: The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
• Immunogen: A synthetic peptide corresponding to the C-terminus of human FOXP1 protein. This sequence is identical to human, mouse, rat, bovine and chicken
• Purification: Affinity Purified
• Concentration: 100ug/200ul
• Specificity: FOXP1
• Formulation: This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Application Info: WB: 0.1-1 ug/ml | ELISA: 0.01-0.1 ug/ml | IP: 2-5 ug/ml | IHC: 2-10 ug/ml | FC: Not tested
• Reference: Kristen Jepsen, et al, CoopeRative regulation in development by SMRT and FOXP1 (2008), GENES & DEVELOPMENT 22:740-745.
  

Target Info

• Gene Symbol: FOXP1
• Gene Full Name: forkhead box P1
• Alias Symbols: 12CC4;fork head-related protein like B;forkhead box protein P1;glutamine-rich factor 1;hFKH1B;HSPC215;mac-1-regulated forkhead;MFH;QRF1.
• NCBI Gene Id: 27086
• Description of Target: FOXP1 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
  
• Uniprot ID: Q9H334
• Molecular Weight: 73.3