PROM1 Antibody - Biotin Conjugated (OAAI00380)

Catalog No: OAAI00380

Size:100UG

WB: The tissue lysate derived from mouse kidney was immunoprobed by Rabbit anti-CD133 (Cat#OAAI00379) at 1:500. An immunoreactive band is observed a round ~117kDa. This band is abolished by pre-incubation with immunizing peptide.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Host: Rabbit
• Conjugation: Biotin
• Application: Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot
• Additional Information: Background: CD133, originally known as AC133, is a glycoprotein, also known in humans and rodents as Prominin 1 (PROM1). CD133 is a member of pentaspan transmembrane glycoproteins (5-transmembrane, 5-TM), which specifically localize to cellular protrusions. CD133 is expressed in hemtopoietic stem cells, endothelial progenitor cells, glioblastoma, neuronal and glial stem cells, virous pediatric brain tumors as well as adult kidney, mammary glands, trachea salivary glands, placenta, digestive tract, testes, and some other cell types.
  Positive Control: Kidney Tissue
  Cellular Location: Cell Membrane
• Reconstitution and Storage: The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
• Immunogen: A 18aa synthetic peptide corresponding to C-terminus human CD133.
• Purification: Affinity Purified
• Concentration: 100ug/200ul
• Specificity: PROM1
• Formulation: This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Application Info: WB: 0.1-1 ug/ml | ELISA: 0.01-0.1 ug/ml | IP: 2-5 ug/ml | IHC: 2-10 ug/ml | FC: 0.5-5 ug/106 cells
• Reference: Yin A, et al, AC133, is a novel ,marker for human hematopoietic stem and progenitor cells. Blood 09 (12): 5002-5012 (1997).

Target Info

• Gene Symbol: PROM1
• Gene Full Name: prominin 1
• Alias Symbols: AC133;antigen AC133;CD133;CORD12;hematopoietic stem cell antigen;hProminin;MCDR2;MSTP061;prominin-1;prominin-like protein 1;PROML1;RP41;STGD4.
• NCBI Gene Id: 8842
• Description of Target: CD133, originally known as AC133, is a glycoprotein, also known in humans and rodents as Prominin 1 (PROM1). CD133 is a member of pentaspan transmembrane glycoproteins (5-transmembrane,5-TM), which specifically localize to cellular protrusions. CD133 is expressed in hemtopoietic stem cells, endothelial progenitor cells, glioblastoma, neuronal and glial stem cells, virous pediatric brain tumors as well as adult kidney, mammary gland, trachea salivary glands, placenta, digestive tract, testes, and some other cell types.
• Uniprot ID: O43490
• Molecular Weight: 97