Catalog No: OASE00468 (Formerly GWB-DM1A11)
Size:100ul
Price: $409.00
SKU
OASE00468
Availability: Domestic: within 3-5 days delivery | International: 3-5 days
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Amyloid Oligomers (A11) Antibody (OASE00468)

Datasheets/ManualsPrintable datasheet for OASE00468
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Eukaryote
Product FormatLiquid. PBS, 50% glycerol, 0.09% sodium azide
ClonalityPolyclonal
HostRabbit
ConjugationHRP: Horseradish Peroxidase
ApplicationWB, IHC, ICC, IF, IP, ELISA
Additional InformationCellular Localization: Membrane
Reconstitution and StorageStore at -20C. Shipping with Blue Ice or 4C.
ImmunogenSynthetic molecular mimic of soluble oligomers
PurificationProtein A Purified
SpecificityRecognizes all types of amyloid oligomers. Appears to recog a peptide backbone epitope common to amyloid oligomers, but not found in native proteins, amyloidogenic monomer or mature amyloid fibrils.
DilutionThe suggested dilution for the current lot of SPC-506 in Western Blot and Dot Blot is 1:100; optimal dilutions for assays should be determined by the user.
Application InfoThe suggested dilution for the current lot in Western Blot and Dot Blot is 1:100; optimal dilutions for assays should be determined by the user.Note: A 1:200 dilution of the product was sufficient for detection of amyloid oligomers in 10 ug of mouse brain lysates by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
Storage BufferPBS, 50% glycerol, 0.09% sodium azide
DescriptionAmyloid monomeric proteins can sometimes oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibres (1, 2). These include the amyloid-β peptide plaques and tau neurofibrillary tangles in senile plaques of Alzheimer's symptomology, the deposition of α-synuclein in the Lewy bodies of Parkinson's disease, and accumulation of polyglutamine-containing aggregates in Huntington's disease (2, 3).
Gene SymbolAmyloid
Gene Full Nameeukaryotic translation initiation factor 3 subunit p42
Alias SymbolsAmyloid Oligomer alpha beta, A11, Amyloid Oligomer AlphaBeta, APP
NCBI Gene Id8666
Description of TargetAmyloid monomeric proteins can sometimes oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibres. These include the amyloid-beta peptide plaques and tau neurofibrillary tangles in senile plaques of Alzheimer's symptomology, the deposition of alpha-synuclein in the Lewy bodies of Parkinson’s disease, and accumulation of polyglutamine-containing aggregates in Huntington’s disease.
Uniprot IDP05067
Nucleotide Accession #NM_000484.2
  1. What is the species homology for "Amyloid Oligomers (A11) Antibody (OASE00468)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Eukaryote".

  2. How long will it take to receive "Amyloid Oligomers (A11) Antibody (OASE00468)"?

    This item is available "Domestic: within 3-5 days delivery | International: 3-5 days".

  3. What buffer format is "Amyloid Oligomers (A11) Antibody (OASE00468)" provided in?

    This item is provided in "Liquid. PBS, 50% glycerol, 0.09% sodium azide ".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Amyloid Oligomers (A11) Antibody (OASE00468)"?

    This target may also be called "Amyloid Oligomer alpha beta, A11, Amyloid Oligomer AlphaBeta, APP" in publications.

  5. What is the shipping cost for "Amyloid Oligomers (A11) Antibody (OASE00468)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Amyloid Oligomers (A11) Antibody (OASE00468)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Amyloid Oligomers (A11) Antibody (OASE00468)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Amyloid Oligomers (A11) Antibody (OASE00468)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "Amyloid"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "Amyloid"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "Amyloid"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "Amyloid"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "Amyloid"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "Amyloid"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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