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- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for OASE00468 |
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| Predicted Species Reactivity | Human, Mouse, Rat, Eukaryote |
|---|---|
| Product Format | Liquid. PBS, 50% glycerol, 0.09% sodium azide |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | WB, IHC, ICC, IF, IP, ELISA |
| Additional Information | Cellular Localization: Membrane Certificate of Analysis: A 1:200 dilution of SPC-506 was sufficient for detection of amyloid oligomers in 10 ug of mouse brain lysates by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody. |
| Reconstitution and Storage | Store at -20°C for 1 year. |
| Immunogen | Synthetic molecular mimic of soluble oligomers |
| Purification | Protein A Purified |
| Concentration | Varies by lot. See vial for concentration. |
| Specificity | Recognizes all types of amyloid oligomers. Appears to recog a peptide backbone epitope common to amyloid oligomers, but not found in native proteins, amyloidogenic monomer or mature amyloid fibrils. |
| Application Info | The suggested dilution for the current lot of OASE00468 in Western Blot and Dot Blot is 1:100; optimal dilutions for assays should be determined by the user. |
| Storage Buffer | PBS, 50% glycerol, 0.09% sodium azide |
| Description | Amyloid monomeric proteins can sometimes oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibres (1, 2). These include the amyloid-β peptide plaques and tau neurofibrillary tangles in senile plaques of Alzheimer's symptomology, the deposition of α-synuclein in the Lewy bodies of Parkinson's disease, and accumulation of polyglutamine-containing aggregates in Huntington's disease (2, 3). |
| Gene Symbol | Amyloid |
|---|---|
| Gene Full Name | eukaryotic translation initiation factor 3 subunit p42 |
| Alias Symbols | Amyloid Oligomer alpha beta, A11, Amyloid Oligomer AlphaBeta, APP |
| NCBI Gene Id | 8666 |
| Description of Target | Amyloid monomeric proteins can sometimes oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibres. These include the amyloid-beta peptide plaques and tau neurofibrillary tangles in senile plaques of Alzheimer's symptomology, the deposition of alpha-synuclein in the Lewy bodies of Parkinson’s disease, and accumulation of polyglutamine-containing aggregates in Huntington’s disease. |
| Uniprot ID | P05067 |
| Nucleotide Accession # | NM_000484.2 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Amyloid Oligomers (A11) Antibody (OASE00468)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Eukaryote".
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How long will it take to receive "Amyloid Oligomers (A11) Antibody (OASE00468)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "Amyloid Oligomers (A11) Antibody (OASE00468)" provided in?
This item is provided in "Liquid. PBS, 50% glycerol, 0.09% sodium azide ".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Amyloid Oligomers (A11) Antibody (OASE00468)"?
This target may also be called "Amyloid Oligomer alpha beta, A11, Amyloid Oligomer AlphaBeta, APP" in publications.
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What is the shipping cost for "Amyloid Oligomers (A11) Antibody (OASE00468)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Amyloid Oligomers (A11) Antibody (OASE00468)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Amyloid Oligomers (A11) Antibody (OASE00468)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Amyloid Oligomers (A11) Antibody (OASE00468)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "Amyloid"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "Amyloid"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "Amyloid"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "Amyloid"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "Amyloid"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "Amyloid"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
