ALOX15B Recombinant Protein (OPCD01258)

Catalog No: OPCD01258

ALOX15B Recombinant Protein (OPCD01258) using SDS-PAGE

ALOX15B Recombinant Protein (OPCD01258) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Arg253-Glu490
  Subcellular Location: Nucleus. Cytoplasm, cytosol. Cell membrane. Cytoskeleton. Membrane; Peripheral membrane protei
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: ALOX15B
• Gene Full Name: arachidonate 15-lipoxygenase type B
• Alias Symbols: 15-lipoxygenase 2;15-LOX-2;15-LOX-B;15S-lipoxygenase;arachidonate 15-lipoxygenase 2;arachidonate 15-lipoxygenase type II;arachidonate 15-lipoxygenase, second type;arachidonate omega(6) lipoxygenase;linoleate 13-lipoxygenase 15-LOb;polyunsaturated fatty acid lipoxygenase ALOX15B.
• NCBI Gene Id: 247
• Protein Name: Arachidonate 15-lipoxygenase B
• Description of Target: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells.
• Uniprot ID: O15296
• Protein Accession #: NP_001034219.1
• Nucleotide Accession #: NM_001039130.1
• Protein Size (# AA): Arg253~Glu490
• Molecular Weight: 27kDa