AHRR Recombinant Protein (OPCD00244)

Catalog No: OPCD00244

AHRR Recombinant Protein (OPCD00244) using SDS-PAGE

AHRR Recombinant Protein (OPCD00244) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Met1-Pro182
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 90%
• Source: E.coli
• Tag: N-terminal His and GST Tag

Target Info

• Gene Symbol: AHRR
• Gene Full Name: aryl-hydrocarbon receptor repressor
• Alias Symbols: AHH;AHHR;ahR repressor;aryl hydrocarbon hydroxylase regulator;aryl hydrocarbon receptor repressor;bHLHe77;class E basic helix-loop-helix protein 77;dioxin receptor repressor.
• NCBI Gene Id: 57491
• Protein Name: Aryl hydrocarbon receptor repressor
• Description of Target: Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.
• Uniprot ID: A9YTQ3
• Protein Accession #: NP_001229341.1
• Nucleotide Accession #: NM_001242412.1
• Protein Size (# AA): Met1~Pro182
• Molecular Weight: 50kDa