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ADGRL1 Antibody - C-terminal region (ARP65781_P050)

100 ul
$289.00
In Stock

Conjugation Options

ARP65781_P050-FITC Conjugated

ARP65781_P050-HRP Conjugated

ARP65781_P050-Biotin Conjugated

Gene Symbol:
ADGRL1
NCBI Gene Id:
22859
Official Gene Full Name:
adhesion G protein-coupled receptor L1
Protein Name:
adhesion G protein-coupled receptor L1
Swissprot Id:
O94910
Protein Accession #:
AAH07587
Nucleotide Accession #:
NM_001008701
Alias Symbols:
CL1, LEC2, CIRL1, LPHN1
Replacement Item:
This antibody may replace item sc-34484 from Santa Cruz Biotechnology.
Description of Target:
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.
Protein Size (# AA):
839
Molecular Weight:
95kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ADGRL1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ADGRL1.
Immunogen:
The immunogen is a synthetic peptide directed towards the C-terminal region of Human LPHN1
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rat: 100%
Complete computational species homology data:
Anti-LPHN1 (ARP65781_P050)
Peptide Sequence:
Synthetic peptide located within the following region: YSLRSGDFPPGDGGPEPPRGRNLADAAAFEKMIISELVHNNLRGSSSAAK
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
PSMA3; ELAVL1; UBC; CACNA1A; APC; ANKS1A; SHANK1; SHANK2; DLG4; DLG3; ROS1;
Blocking Peptide:
For anti-ADGRL1 (ARP65781_P050) antibody is Catalog # AAP65781
Datasheets/Manuals:
Printable datasheet for anti-ADGRL1 (ARP65781_P050) antibody

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