| Product Number |
ARP65781_P050 |
| Product Page |
www.avivasysbio.com/adgrl1-antibody-c-terminal-region-arp65781-p050.html |
| Name |
ADGRL1 Antibody - C-terminal region (ARP65781_P050) |
| Protein Size (# AA) |
839 amino acids |
| Molecular Weight |
95kDa |
| NCBI Gene Id |
22859 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
adhesion G protein-coupled receptor L1 |
| Alias Symbols |
CL1, LEC2, CIRL1, LPHN1 |
| Peptide Sequence |
Synthetic peptide located within the following region: YSLRSGDFPPGDGGPEPPRGRNLADAAAFEKMIISELVHNNLRGSSSAAK |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms. |
| Protein Interactions |
PSMA3; ELAVL1; UBC; CACNA1A; APC; ANKS1A; SHANK1; SHANK2; DLG4; DLG3; ROS1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-ADGRL1 (ARP65781_P050) antibody |
| Blocking Peptide |
For anti-ADGRL1 (ARP65781_P050) antibody is Catalog # AAP65781 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C-terminal region of Human LPHN1 |
| Uniprot ID |
O94910 |
| Protein Name |
adhesion G protein-coupled receptor L1 |
| Protein Accession # |
AAH07587 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001008701 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
ADGRL1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rat: 100% |
| Image 1 | Human HeLa
 | WB Suggested Anti-LPHN1 Antibody
Titration: 1.0 ug/ml
Positive Control: Hela Whole Cell |
|
|
