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Datasheets/Manuals | Printable datasheet for ADAMTS4 Antibody (OACA02541) (OACA02541) |
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Predicted Species Reactivity | Human|Mouse |
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Product Format | Liquid |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot |
Reconstitution and Storage | -20°C or -80°C |
Immunogen | Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 4 protein (213-319AA) |
Purification | Protein G Purified |
Concentration | 4 mg/ml |
Purity | > 95% |
Application Info | WB: 1:500~5000 IHC: 1:50~500 |
Reference | [1]"An alternative spliced transcript of ADAMTS4 is present in human synovium from OA patients."Wainwright S.D., Bondeson J., Hughes C.E. Matrix Biol. 25:317-320(2006). [2]"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E. Gray A.M.Genome Res. 13:2265-2270(2003). [3]"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. Bentley D.R. Nature 441:315-321(2006). |
Gene Symbol | ADAMTS4 |
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Gene Full Name | ADAM metallopeptidase with thrombospondin type 1 motif 4 |
Alias Symbols | A disintegrin and metalloproteinase with thrombospondin motifs 4;a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4;ADAM-TS 4;ADAMTS-2;ADAMTS-4;ADAM-TS4;ADMP-1;aggrecanase-1;epididymis secretory sperm binding protein. |
NCBI Gene Id | 9507 |
Protein Name | A disintegrin and metalloproteinase with thrombospondin motifs 4 |
Description of Target | Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site. |
Uniprot ID | O75173 |
Protein Accession # | NP_001307265 |
Nucleotide Accession # | NM_001320336 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ADAMTS4 Antibody (OACA02541)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
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How long will it take to receive "ADAMTS4 Antibody (OACA02541)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "ADAMTS4 Antibody (OACA02541)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ADAMTS4 Antibody (OACA02541)"?
This target may also be called "A disintegrin and metalloproteinase with thrombospondin motifs 4;a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4;ADAM-TS 4;ADAMTS-2;ADAMTS-4;ADAM-TS4;ADMP-1;aggrecanase-1;epididymis secretory sperm binding protein." in publications.
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What is the shipping cost for "ADAMTS4 Antibody (OACA02541)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ADAMTS4 Antibody (OACA02541)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ADAMTS4 Antibody (OACA02541)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ADAMTS4 Antibody (OACA02541)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ADAMTS4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ADAMTS4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ADAMTS4"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ADAMTS4"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ADAMTS4"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ADAMTS4"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.