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Catalog No: OACA02541
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OACA02541
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Datasheets/ManualsPrintable datasheet for ADAMTS4 Antibody (OACA02541) (OACA02541)
Product Info
Predicted Species ReactivityHuman|Mouse
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Reconstitution and Storage-20°C or -80°C
ImmunogenRecombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 4 protein (213-319AA)
PurificationProtein G Purified
Concentration4 mg/ml
Purity> 95%
Application InfoWB: 1:500~5000
IHC: 1:50~500
Reference[1]"An alternative spliced transcript of ADAMTS4 is present in human synovium from OA patients."Wainwright S.D., Bondeson J., Hughes C.E. Matrix Biol. 25:317-320(2006). [2]"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E. Gray A.M.Genome Res. 13:2265-2270(2003). [3]"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. Bentley D.R. Nature 441:315-321(2006).
Gene SymbolADAMTS4
Gene Full NameADAM metallopeptidase with thrombospondin type 1 motif 4
Alias SymbolsA disintegrin and metalloproteinase with thrombospondin motifs 4;a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4;ADAM-TS 4;ADAMTS-2;ADAMTS-4;ADAM-TS4;ADMP-1;aggrecanase-1;epididymis secretory sperm binding protein.
NCBI Gene Id9507
Protein NameA disintegrin and metalloproteinase with thrombospondin motifs 4
Description of TargetCleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
Uniprot IDO75173
Protein Accession #NP_001307265
Nucleotide Accession #NM_001320336
  1. What is the species homology for "ADAMTS4 Antibody (OACA02541)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".

  2. How long will it take to receive "ADAMTS4 Antibody (OACA02541)"?

    This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".

  3. What buffer format is "ADAMTS4 Antibody (OACA02541)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ADAMTS4 Antibody (OACA02541)"?

    This target may also be called "A disintegrin and metalloproteinase with thrombospondin motifs 4;a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4;ADAM-TS 4;ADAMTS-2;ADAMTS-4;ADAM-TS4;ADMP-1;aggrecanase-1;epididymis secretory sperm binding protein." in publications.

  5. What is the shipping cost for "ADAMTS4 Antibody (OACA02541)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ADAMTS4 Antibody (OACA02541)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ADAMTS4 Antibody (OACA02541)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ADAMTS4 Antibody (OACA02541)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ADAMTS4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ADAMTS4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ADAMTS4"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ADAMTS4"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ADAMTS4"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ADAMTS4"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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