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| Datasheets/Manuals | Printable datasheet for Abca1 Antibody - PE Conjugated (OASA04770) |
|---|
| Predicted Species Reactivity | Mouse |
|---|---|
| Product Format | Lyophilized. Phosphate buffered saline |
| Clonality | Monoclonal |
| Clone | 5A1-1422 |
| Isotype | IgG2a |
| Host | Rat |
| Conjugation | R-PE |
| Application | Flow cytometry |
| Additional Information | Excitation: 496 nm Emission: 578 nm |
| Reconstitution and Storage | 2°C to 8°C |
| Immunogen | ABCA1 transfected HeLa cells. |
| Purification | Protein G Purified |
| Specificity | Rat anti Mouse ABCA1 antibody, clone 5A1.1422 recognizes murine adenosine triphosphate (ATP) Binding cassette transporter 1 (ABCA1). |
| Application Info | FC: Neat Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Optimal dilutions should be determined by the end user. |
| Reference | 1. Zarubica, A. et al. (2007) ABCA1, from pathology to membrane function. Pflugers Arch.453:569-579. 2. Pradel, L.C. et al. (2009) ATP-binding cassette transporter hallmarks tissue macrophages and modulates cytokine-triggered polarization programs. Eur J Immunol. 39 (8): 2270-80. |
| Gene Symbol | Abca1 |
|---|---|
| Alias Symbols | ABC, Abc1, ABC-1 |
| NCBI Gene Id | 11303 |
| Protein Name | ATP-binding cassette sub-family A member 1 |
| Description of Target | The ABC transporters are a large family of conserved proteins that transport a wide variety of molecules across cellular membranes. ABCA1 is a member of the ABC-A sub-family, which acts as a lipid translocator. The molecule was originally identified as a scavenger receptor on macrophages and research shows that ABCA1 also plays a major role in cholesterol metabolism. ABCA1 may play an important role in protecting against cardiovascular disease. Mutations in ABCA1 gene have been associated with Tangier disease, a genetic disorder of lipid metabolism, and the more common Familial HDL deficiency, presenting with many of the same symptoms. |
| Uniprot ID | P41233 |
| Protein Accession # | NP_038482.3 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Abca1 Antibody - PE Conjugated (OASA04770)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse".
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How long will it take to receive "Abca1 Antibody - PE Conjugated (OASA04770)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "Abca1 Antibody - PE Conjugated (OASA04770)" provided in?
This item is provided in "Lyophilized. Phosphate buffered saline".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Abca1 Antibody - PE Conjugated (OASA04770)"?
This target may also be called "ABC, Abc1, ABC-1" in publications.
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What is the shipping cost for "Abca1 Antibody - PE Conjugated (OASA04770)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Abca1 Antibody - PE Conjugated (OASA04770)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Abca1 Antibody - PE Conjugated (OASA04770)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Abca1 Antibody - PE Conjugated (OASA04770)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ABCA1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ABCA1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ABCA1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ABCA1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ABCA1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ABCA1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
