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- $55: Antibody & Protein in US
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| Datasheets/Manuals | Printable datasheet for anti-SRY (OAAB19787) antibody |
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| Predicted Species Reactivity | Human |
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| Product Format | Liquid 0.01M PBS (pH 7.2) with 0.1% sodium azide and 50% glycerol |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB |
| Additional Information | Cellular Location: Nucleus speckle. Cytoplasm. Nucleus. Note=Acetylation contributes to its nuclear localization and deacetylation by HDAC3 induces a cytoplasmic delocalization. Colocalizes with SOX6 in speckles. Colocalizes with CAML in the nucleus. Colocalizes in the nucleus with ZNF208 isoform KRAB- O and tyrosine hydroxylase (TH). |
| Reconstitution and Storage | Store at -20°C. Stable for 12 months from date of reciept. |
| Immunogen | KLH conjugated synthetic peptide derived from human SRY. Loc: 31-90aa |
| Concentration | 1 mg/ml |
| Application Info | WB: 1:1000 |
| Reference | Sinclair A.H.,et al.Nature 346:240-244(1990). Su H.,et al.Am. J. Hum. Genet. 52:24-38(1993). Behlke M.A.,et al.Genomics 17:736-739(1993). Whitfield L.S.,et al.Genomics 27:306-311(1995). Ferrari S.,et al.EMBO J. 11:4497-4506(1992). |
| Gene Symbol | SRY |
|---|---|
| Alias Symbols | TDF, TDY, SRXX1, SRXY1 |
| NCBI Gene Id | 6736 |
| Description of Target | Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. In male adult brain involved in the maintenance of motor functions of dopaminergic neurons. Involved in different aspects of gene regulation including promoter activation or repression. Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. |
| Uniprot ID | Q05066 |
| Molecular Weight | 24 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "SRY Antibody (OAAB19787)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "SRY Antibody (OAAB19787)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "SRY Antibody (OAAB19787)" provided in?
This item is provided in "Liquid 0.01M PBS (pH 7.2) with 0.1% sodium azide and 50% glycerol".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "SRY Antibody (OAAB19787)"?
This target may also be called "TDF, TDY, SRXX1, SRXY1" in publications.
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What is the shipping cost for "SRY Antibody (OAAB19787)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "SRY Antibody (OAAB19787)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "SRY Antibody (OAAB19787)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "24 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "SRY Antibody (OAAB19787)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "SRY"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "SRY"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "SRY"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "SRY"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "SRY"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "SRY"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
