SNCA Protein (OPPA01305)

Catalog No: OPPA01305 (Formerly GWB-99A1F8)

Size:20UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: The protein (1mg/ml) contains 20mM Tris-HCl buffer (pH 7.5), 0.1M NaCl and 1mM MgCl2. Physical appearance: Sterile filtered colorless solution.
• Host: E. Coli
  Product Introduction: a-Synuclein (amino acids 1-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. a-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Moreover, recent studies have shown that a-synuclein has chaperone activity and that this activity is lost upon removing its C-terminal acidic tail (amino acids 96-140).
• Reconstitution and Storage: Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Avoid multiple freeze-thaw cycles.
• Purity: Greater than 95.0% as determined by SDS-PAGE.
• Peptide Sequence: MDVFMKGLSK/ AKEGVVAAAE/ KTKQGVAEAA/ GKTKEGVLYV/ GSKTKEGVVH/GVATVAEKTK/ EQVTNVGGAV/VTGVTAVAQK/TVEGAGSIAA/ ATGFVKKDQL/ GKNEEGAPQE/ GILEDMPVDP/DNEAYEMPSE/EGYQDYEPEA.

Target Info

• Gene Symbol: SNCA
• Alias Symbols: PD1, NACP, PARK1, PARK4
• NCBI Gene Id: 6622
• Protein Name: Alpha-synuclein
• Description of Target: a-Synuclein Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain of 140 amino acids having a molecular mass of 14.4kDa. The Recombinant Human a-Synuclein is purified by proprietary chromatographic techniques.
• Uniprot ID: P37840
• Protein Accession #: NP_000336.1
• Protein Size (# AA): Recombinant