SLC1A1 Recombinant Protein (OPCD02829)

Catalog No: OPCD02829

SLC1A1 Recombinant Protein (OPCD02829) using SDS-PAGE

SLC1A1 Recombinant Protein (OPCD02829) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ser115-Gly209
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: >95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: SLC1A1
• Gene Full Name: solute carrier family 1 member 1
• Alias Symbols: DCBXA;EAAC1;EAAT3;excitatory amino acid carrier 1;excitatory amino acid transporter 3;Excitatory amino-acid carrier 1;neuronal and epithelial glutamate transporter;SCZD18;sodium-dependent glutamate/aspartate transporter 3;solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1;Solute carrier family 1 member 1.
• NCBI Gene Id: 6505
• Protein Name: Excitatory amino acid transporter 3
• Description of Target: Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7914198, PubMed:7521911, PubMed:8857541, PubMed:26690923, PubMed:21123949). Can also transport L-cysteine (PubMed:21123949). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:7521911, PubMed:8857541, PubMed:26690923). Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:8857541, PubMed:26690923). Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli (PubMed:21123949). Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity). Negatively regulated by ARL6IP5 (By similarity).
• Uniprot ID: P43005
• Protein Accession #: NP_004161.4
• Nucleotide Accession #: NM_004170.5
• Protein Size (# AA): Ser115~Gly209
• Molecular Weight: 14kDa