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SALL3 Antibody - N-terminal region (ARP39971_P050)

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100 ul
$289.00
In Stock
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Conjugation Options

ARP39971_P050-FITC Conjugated

ARP39971_P050-HRP Conjugated

ARP39971_P050-Biotin Conjugated

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Gene Symbol:
SALL3
Official Gene Full Name:
spalt like transcription factor 3
NCBI Gene Id:
27164
Protein Name:
Sal-like protein 3
Swissprot Id:
Q9BXA9
Protein Accession #:
NP_741996
Nucleotide Accession #:
NM_171999.3
Alias Symbols:
ZNF796
Description of Target:
This gene encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis.
Protein Size (# AA):
1300
Molecular Weight:
143 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SALL3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SALL3.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human SALL3
Predicted Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Cow: 79%; Dog: 79%; Human: 100%; Mouse: 100%; Pig: 85%; Rat: 100%; Zebrafish: 93%
Complete computational species homology data:
Anti-SALL3 (ARP39971_P050)
Peptide Sequence:
Synthetic peptide located within the following region: MSRRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEET
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
DNMT3A; CHD7; UBC; SOX2;
Blocking Peptide:
For anti-SALL3 (ARP39971_P050) antibody is Catalog # AAP39971
Datasheets/Manuals:
Printable datasheet for anti-SALL3 (ARP39971_P050) antibody

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