Size:100 ul
Special Price $229.00 Regular Price $289.00
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SKU
ARP39971_P050
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Conjugation Options

ARP39971_P050-FITC Conjugated

ARP39971_P050-HRP Conjugated

ARP39971_P050-Biotin Conjugated

SALL3 Antibody - N-terminal region (ARP39971_P050)

Catalog#: ARP39971_P050
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More Information
Predicted Species ReactivityHuman
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human SALL3
PurificationAffinity purified
Predicted Homology Based on Immunogen SequenceCow: 79%; Dog: 79%; Human: 100%; Mouse: 100%; Pig: 85%; Rat: 100%; Zebrafish: 93%
Complete computational species homology dataAnti-SALL3 (ARP39971_P050)
Peptide SequenceSynthetic peptide located within the following region: MSRRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEET
ConcentrationBatch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking PeptideFor anti-SALL3 (ARP39971_P050) antibody is Catalog # AAP39971
Datasheets/ManualsPrintable datasheet for anti-SALL3 (ARP39971_P050) antibody
Gene SymbolSALL3
Official Gene Full Namespalt like transcription factor 3
Alias SymbolsZNF796
NCBI Gene Id27164
Protein NameSal-like protein 3
Description of TargetThis gene encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis.
Swissprot IdQ9BXA9
Protein Accession #NP_741996
Nucleotide Accession #NM_171999.3
Protein Size (# AA)1300
Molecular Weight143 kDa
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express SALL3.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express SALL3.
Protein InteractionsDNMT3A; CHD7; UBC; SOX2;
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