RPL13A Antibody (OACA10449)

Catalog No: OACA10449

Immunofluorescent analysis of A549 cells at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Immunofluorescent analysis of A549 cells at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence
• Reconstitution and Storage: -20°C or -80°C
• Immunogen: Recombinant Human 60S ribosomal protein L13a protein (63-190AA)
• Purification: Protein G Purified
• Preservative: 0.03% Proclin 300
• Formulation: 50% Glycerol, 0.01M PBS, pH 7.4
• Purity: >95%

Target Info

• Gene Symbol: RPL13A
• Gene Full Name: ribosomal protein L13a
• Alias Symbols: 23 kDa highly basic protein;60S ribosomal protein L13a;epididymis secretory sperm binding protein;L13A;large ribosomal subunit protein uL13;tissue specific transplantation antigen 1;TSTA1.
• NCBI Gene Id: 23521
• Protein Name: 60S ribosomal protein L13a
• Description of Target: Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA.
• Uniprot ID: P40429
• Protein Accession #: NP_001257420
• Nucleotide Accession #: NM_001270491