PMS2 Antibody - middle region (OASG05997)

Catalog No: OASG05997

Size:100 uL

Western Blot using HeLa

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC, IF
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the Internal region of human PMS2. Location: 430-510aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: PMS2 Polyclonal Antibody detects endogenous levels of PMS2 protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000;

Target Info

• Gene Symbol: PMS2
• Gene Full Name: PMS1 homolog 2, mismatch repair system component
• Alias Symbols: MLH4, PMSL2, HNPCC4, MMRCS4, PMS2CL
• NCBI Gene Id: 5395;
• Description of Target: This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.
• Uniprot ID: P54278
• Molecular Weight: 85 kDa