PLCL1 Antibody - N-terminal region (OAAB05445)

Catalog No: OAAB05445

Size:400UL

Western blot analysis of PLCL1 Antibody (N-term) in Jurkat cell lysates (35ug/lane). PLCL1 (arrow) was detected using the purified Pab.

PLCL1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

PLCL1 Antibody (N-term) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: FC,WB
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This PLCL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-176 amino acids from the N-terminal region of human PLCL1.
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  PLCL1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

• Application Info: WB: 1:1000
  FC: 1:10~50
• Other Applications Image 1 Data: PLCL1 Antibody (N-term) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Target Info

• Gene Symbol: PLCL1
• Alias Symbols: 130kDa-Ins(1,4,5)P3 binding protein, C230017K02Rik, inactive phospholipase C-like protein 1, p130, phospholipase C-deleted in lung carcinoma, phospholipase C-like 1, phospholipase C-related but catalytically inactive protein, phospholipase C, epsilon, phospholipase C, eta 2 pseudogene, PL, PLC-L, PLC-L1, PLCE, PLCL, PLDL1, PPP1R127, PR, PRIP, PRIP-1, PRIP1, protein phosphatase 1, regulatory subunit 127.
• NCBI Gene Id: 227120|5334|84587
• Protein Name: Inactive phospholipase C-like protein 1|inactive phospholipase C-like protein 1 [Homo sapiens]
• Description of Target: Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C.|Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor. Acts as a inhibitor of PPP1C (By similarity). Involved in the assembly and/or the trafficking of gamma-2 subunit-containing GABA A receptors.|Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor. Acts as a inhibitor of PPP1C.
• Uniprot ID: Q15111|Q3USB7|Q62688
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_006217.3
• Molecular Weight: 122728