Catalog No: ARP51642_P050
Price: $0.00
SKU
ARP51642_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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Datasheets/ManualsPrintable datasheet for ARP51642_P050
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human PAXIP1
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Peptide SequenceSynthetic peptide located within the following region: MFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVP
Concentration0.5 mg/ml
Blocking PeptideCatalog # AAP51642 (Previous Catalog # AAPP30059)
Sample Type Confirmation

PAXIP1 is supported by BioGPS gene expression data to be expressed in 721_B

Gene SymbolPAXIP1
Gene Full NamePAX interacting (with transcription-activation domain) protein 1
Alias SymbolsPTIP, TNRC2, CAGF28, CAGF29, PACIP1, PAXIP1L
NCBI Gene Id22976
Protein NamePAX-interacting protein 1
Description of TargetPAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation.
Uniprot IDQ6ZW49
Protein Accession #EAX04525
Nucleotide Accession #NM_007349
Protein Size (# AA)697
Molecular Weight74kDa
Protein InteractionsMAPRE2; POM121; NXT1; PPARG; XAGE1E; SMAD2; SPATA18; COMTD1; BTBD16; DIS3L; LACTB; HNRNPLL; ZNF251; ZNF622; BTBD6; C7orf50; FAM175A; TMEM120A; FAHD1; TM2D3; ATHL1; CENPU; DYNC2H1; BRCC3; KRI1; ANAPC1; NOM1; POLR1E; NCAPG; AASDHPPT; RBM25; CATSPERG; WDR48;
  1. What is the species homology for "PAXIP1 Antibody - N-terminal region (ARP51642_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "PAXIP1 Antibody - N-terminal region (ARP51642_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "PAXIP1 Antibody - N-terminal region (ARP51642_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PAXIP1 Antibody - N-terminal region (ARP51642_P050)"?

    This target may also be called "PTIP, TNRC2, CAGF28, CAGF29, PACIP1, PAXIP1L" in publications.

  5. What is the shipping cost for "PAXIP1 Antibody - N-terminal region (ARP51642_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PAXIP1 Antibody - N-terminal region (ARP51642_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PAXIP1 Antibody - N-terminal region (ARP51642_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "74kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PAXIP1 Antibody - N-terminal region (ARP51642_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PAXIP1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PAXIP1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PAXIP1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PAXIP1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PAXIP1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PAXIP1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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