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Datasheets/Manuals | Printable datasheet for PARD3 Antibody (OAAF02569) |
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Predicted Species Reactivity | Human|Mouse|Rat |
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Product Format | Liquid |
Clonality | Polyclonal |
Host | Rabbit |
Application | Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot |
Reconstitution and Storage | -20°C |
Immunogen | The antiserum was produced against synthesized peptide derived from human PARD3. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Specificity | PARD3 antibody detects endogenous levels of total PARD3 protein. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Dilution | The optimal working dilution should be determined by the end user. |
Application Info | WB: 1:500~1:3000; IF: 1:100~1:500; ELISA: 1:20000 |
Reference | Joberty G., Nat. Cell Biol. 2:531-539(2000). Fang C.M., Cell Res. 11:223-229(2001). Kohjima M., Biochem. Biophys. Res. Commun. 299:641-646(2002). |
Gene Symbol | PARD3 |
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Gene Full Name | par-3 family cell polarity regulator |
Alias Symbols | ASIP;atypical PKC isotype-specific interacting protein;Atypical PKC isotype-specific-interacting protein;Baz;bazooka;CTCL tumor antigen se2-5;PAR3;par-3 family cell polarity regulator alpha;par-3 partitioning defective 3 homolog;PAR3alpha;PAR3-alpha;PARD-3;PARD3A;partitioning defective 3 homolog;PPP1R118;protein phosphatase 1, regulatory subunit 118;SE2-5L16;SE2-5LT1;SE2-5T2. |
NCBI Gene Id | 56288 |
Protein Name | Partitioning defective 3 homolog |
Description of Target | Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:27925688, PubMed:10954424). Seems to play a central role in the formation of epithelial tight junctions (PubMed:27925688). Targets the phosphatase PTEN to cell junctions (By similarity). Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly (By similarity). The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10934474). Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (PubMed:19812038, PubMed:27925688). |
Uniprot ID | Q8TEW0 |
Protein Accession # | NP_001171714.1 |
Molecular Weight | 151 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "PARD3 Antibody (OAAF02569)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "PARD3 Antibody (OAAF02569)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "PARD3 Antibody (OAAF02569)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PARD3 Antibody (OAAF02569)"?
This target may also be called "ASIP;atypical PKC isotype-specific interacting protein;Atypical PKC isotype-specific-interacting protein;Baz;bazooka;CTCL tumor antigen se2-5;PAR3;par-3 family cell polarity regulator alpha;par-3 partitioning defective 3 homolog;PAR3alpha;PAR3-alpha;PARD-3;PARD3A;partitioning defective 3 homolog;PPP1R118;protein phosphatase 1, regulatory subunit 118;SE2-5L16;SE2-5LT1;SE2-5T2." in publications.
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What is the shipping cost for "PARD3 Antibody (OAAF02569)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "PARD3 Antibody (OAAF02569)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "PARD3 Antibody (OAAF02569)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "151 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PARD3 Antibody (OAAF02569)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "PARD3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "PARD3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "PARD3"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "PARD3"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "PARD3"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "PARD3"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.