P2RX7 Recombinant Protein (OPCD05941)

Catalog No: OPCD05941

P2RX7 Recombinant Protein (OPCD05941) using SDS-PAGE

P2RX7 Recombinant Protein (OPCD05941) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ser47-Val334
  Subcellular Location: Membrane.
  Isoelectric Point: 8.6
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 150 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: P2RX7
• Gene Full Name: purinergic receptor P2X 7
• Alias Symbols: ATP receptor;P2X purinoceptor 7;P2X7;P2X7 receptor;P2Z receptor;Purinergic receptor;purinergic receptor P2X, ligand gated ion channel, 7;purinergic receptor P2X7 variant A;purnergic receptor P2X 7.
• NCBI Gene Id: 5027
• Protein Name: P2X purinoceptor 7
• Description of Target: Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells (PubMed:21821797, PubMed:23303206).
• Uniprot ID: Q99572
• Protein Accession #: NP_002553.3
• Nucleotide Accession #: NM_002562.5
• Protein Size (# AA): Ser47~Val334
• Molecular Weight: 28/32/35kDa