NR5A2 Recombinant Protein (OPCD00637)

Catalog No: OPCD00637

NR5A2 Recombinant Protein (OPCD00637) using SDS-PAGE

NR5A2 Recombinant Protein (OPCD00637) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Rat|Rattus norvegicus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Met1-Ala205
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: >95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Nr5a2
• Gene Full Name: nuclear receptor subfamily 5, group A, member 2
• Alias Symbols: fetoprotein transcription factor;Ftf;FTZ-F1 beta;FTZ-F1 beta2 protein;liver receptor homolog 1;Lrh-1;nuclear receptor subfamily 5 group A member 2.
• NCBI Gene Id: 60349
• Protein Name: Nuclear receptor subfamily 5 group A member 2
• Description of Target: Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
• Uniprot ID: Q9QWM1
• Protein Accession #: NP_068510.1
• Nucleotide Accession #: NM_021742.1
• Protein Size (# AA): Met1~Ala205
• Molecular Weight: 27kDa