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Now Offering Over 102,157 Antibodies & 44,722 Antigens!

NR5A1 antibody - middle region (ARP31834_P050)

100 ul
$319.00
In Stock

Conjugation Options

ARP31834_P050-FITC Conjugated

ARP31834_P050-HRP Conjugated

ARP31834_P050-Biotin Conjugated

Gene Symbol:
NR5A1
NCBI Gene Id:
2516
Official Gene Full Name:
Nuclear receptor subfamily 5, group A, member 1
Protein Name:
Steroidogenic factor 1
Swissprot Id:
Q13285
Protein Accession #:
NP_004950
Nucleotide Accession #:
NM_004959
Alias Symbols:
AD4BP, ELP, FTZ1, FTZF1, SF-1, SF1, POF7, SPGF8, SRXY3
Replacement Item:
This antibody may replace item sc-10975 from Santa Cruz Biotechnology.
Description of Target:
NR5A1 is an important regulator of steroidogeneisis which is present in human skin and its appendages. It plays a role in regulating p450scc expression with TReP-132 and CBP/p300. The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Size (# AA):
461
Molecular Weight:
52kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express NR5A1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express NR5A1.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human NR5A1
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
Predicted Homology Based on Immunogen Sequence:
Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 79%; Rabbit: 85%; Rat: 92%; Sheep: 85%
Complete computational species homology data:
Anti-NR5A1 (ARP31834_P050)
Peptide Sequence:
Synthetic peptide located within the following region: AVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGP
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
NCK2; NR0B1; RAD54L2; THOC2; ALYREF; EIF4A3; DDX39B; UBC; BARD1; ELAVL1; TCF7L2; CTNNB1; CREBBP; CXXC1; PNRC2; SOX8; PIAS1; ZNF653; TRERF1; EDF1; GATA4; GTF2B; SOX2; SOX9; TBX19; NCOA1; NRIP1; PITX1; SMARCD3; PROX1; AR; SP1; NFYA; MAPK1; JUN; NFKB2;
Blocking Peptide:
For anti-NR5A1 (ARP31834_P050) antibody is Catalog # AAP31834 (Previous Catalog # AAPP07402)
Datasheets/Manuals:
Printable datasheet for anti-NR5A1 (ARP31834_P050) antibody
Sample Type Confirmation:

NR5A1 is supported by BioGPS gene expression data to be expressed in HepG2

Target Reference:
Li,L.A., et al., (2004) J. Steroid Biochem. Mol. Biol. 91 (1-2), 11-20

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