NAB2 Antibody - C-terminal region (ARP38716_P050)

Catalog No: ARP38716_P050

WB Suggested Anti-NAB2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human heart

Host: Mouse
Target Name: NAB2
Sample Tissue: Mouse Pancreas
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human, Mouse
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NAB2
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: GRLSPCVPAKPPLAEFEEGLLDRCPAPGPHPALVEGRRSSVKVEAEASRQ
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-NAB2 (ARP38716_P050) antibody is Catalog # AAP38716 (Previous Catalog # AAPP20923)
• Reference: Olsen,J.V., (2006) Cell 127 (3), 635-648

Target Info

• Gene Symbol: NAB2
• Gene Full Name: NGFI-A binding protein 2 (EGR1 binding protein 2)
• Alias Symbols: MADER
• NCBI Gene Id: 4665
• Protein Name: NGFI-A-binding protein 2
• Description of Target: NAB2 is a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize withThis gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: Q15742
• Protein Accession #: NP_005958
• Nucleotide Accession #: NM_005967
• Protein Size (# AA): 525
• Molecular Weight: 56kDa
• Protein Interactions: AES; KRT40; ZMYND19; TGIF2LY; TCHP; CCDC33; GCC1; LENG1; SCNM1; ZBED8; TTC19; CCHCR1; NME7; RBPMS; MORF4L1; JAKMIP2; RFC5; PIN1; PHF1; NEDD9; NAB2; MDFI; MCM7; PHOSPHO2; SUMO1P1; NOTCH2NL; KRTAP10-3; KRTAP10-8; TCEANC; CWF19L2; DGCR6; MAPK3; VBP1; TLN1; S