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MXD4 antibody - N-terminal region (ARP32777_P050)

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100 ul
$319.00
In Stock

Conjugation Options

ARP32777_P050-FITC Conjugated

ARP32777_P050-HRP Conjugated

ARP32777_P050-Biotin Conjugated

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Gene Symbol:
MXD4
NCBI Gene Id:
10608
Official Gene Full Name:
MAX dimerization protein 4
Protein Name:
Max dimerization protein 4
Swissprot Id:
Q14582
Protein Accession #:
NP_006445
Nucleotide Accession #:
NM_006454
Alias Symbols:
MAD4, MST149, MSTP149, bHLHc12
Description of Target:
MXD4 is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
Protein Size (# AA):
209
Molecular Weight:
24kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB, IHC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express MXD4.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express MXD4.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human MXD4
Species Reactivity:
Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Sheep
Predicted Homology Based on Immunogen Sequence:
Cow: 93%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Sheep: 93%
Complete computational species homology data:
Anti-MXD4 (ARP32777_P050)
Peptide Sequence:
Synthetic peptide located within the following region: SLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNN
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
TCP10L; UBC; SHBG; SIN3A; MLX; MAX; SMC3;
Blocking Peptide:
For anti-MXD4 (ARP32777_P050) antibody is Catalog # AAP32777 (Previous Catalog # AAPP03792)
Datasheets/Manuals:
Printable datasheet for anti-MXD4 (ARP32777_P050) antibody
Target Reference:
Jiang,D.J., et al., (2004) J. Biochem. Mol. Biol. 37 (4), 402-407

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