MAPK8IP3 Antibody - middle region (OASG04023)

Catalog No: OASG04023

Size:100 uL

Western Blot using HeLa

Western Blot using Jurkat

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC, IF
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the Internal region of human JIP-3. Location: 590-670aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: JIP-3 Polyclonal Antibody detects endogenous levels of JIP-3 protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000;

Target Info

• Gene Symbol: MAPK8IP3
• Gene Full Name: mitogen-activated protein kinase 8 interacting protein 3
• Alias Symbols: syd, JIP3, SYD2, JIP-3, JSAP1, NEDBA
• NCBI Gene Id: 23162; 30957;
• Description of Target: The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
• Uniprot ID: Q9UPT6, Q9ESN9
• Molecular Weight: 147 kDa