MAP2K6 Antibody (Phospho-Ser207) (OASG04489)

Catalog No: OASG04489

Size:100 uL

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human MEK-6 around the phosphorylation site of S207.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Ser207
• Specificity: Phospho-MEK-6 (S207) Polyclonal Antibody detects endogenous levels of MEK-6 protein only when phosphorylated at S207.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Target Info

• Gene Symbol: MAP2K6
• Gene Full Name: mitogen-activated protein kinase kinase 6
• Alias Symbols: MEK6, MKK6, MAPKK6, PRKMK6, SAPKK3, SAPKK-3
• NCBI Gene Id: 5608; 26399;
• Description of Target: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
• Uniprot ID: P52564, P70236
• Molecular Weight: 39 kDa