LTBP4 Antibody (OAGA00117)

Catalog No: OAGA00117

Size:100 ul

LTBP4 antibody [N1N2], N-term detects LTBP4 protein by Western blot analysis.
A. 30 ug K562 whole cell lysate/extract
5 % SDS-PAGE
LTBP4 antibody [N1N2], N-term (OAGA00117) dilution: 1:1000

Sample (50 ug of whole cell lysate)
A: Mouse brain
5% SDS PAGE
OAGA00117 diluted at 1:1000

LTBP4 antibody [N1N2], N-term detects LTBP4 protein at cytosol on Adrenal Gland Tumor by immunohistochemical analysis.
Sample: Paraffin-embedded Adrenal Gland Tumor.
LTBP4 antibody [N1N2], N-term (OAGA00117) dilution: 1:250.

Immunofluorescence analysis of methanol-fixed A431, using LTBP4(OAGA00117) antibody at 1:200 dilution.

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. 1X PBS, 1% BSA, 20% glycerol (pH 7) with 0.025% Proclin300 as a preservative
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: ICC, IF, IHC-FFPE, WB
  Positive Controls: K562, mouse brain
  Cellular Localization: Secreted, extracellular space, extracellular matrix
• Reconstitution and Storage: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below.
  Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human LTBP4. The exact sequence is proprietary.
• Purification: Purified by antigen-affinity chromatography.
• Predicted Homology Based on Immunogen Sequence: Rat (97%)
• Concentration: 0.25 mg/ml
• Application Info: ICC/IF: 1:100~1,000
  IHC-P: 1:100~1,000
  WB: 1:500~3,000
  Not tested in other applications.

Target Info

• Gene Symbol: LTBP4
• Gene Full Name: Latent-transforming growth factor beta-binding protein 4
• Alias Symbols: ARCL1C, LTBP-4, LTBP4L, LTBP4S
• NCBI Gene Id: 8425
• Protein Name: Latent-transforming growth factor beta-binding protein 4
• Description of Target: Transforming growth factor-beta, or TGFB (see TGFB1; MIM 190180), remains biologically latent after secretion, blocked from activity by its N-terminal propeptide (the latency-associated peptide, or LAP). TGFB is activated by its dissociation from LAP. The latent form of TGFB is secreted in association with a latent TGFB-binding protein, or LTBP (see LTBP1; MIM 150390), and assembled into the extracellular matrix. LTBPs are mainly composed of epidermal growth factor (EGF; MIM 131530)-like repeats and protein domains with 8-cysteine repeats, both of which are also found in fibrillins (e.g., MIM 134797). See Oklu and Hesketh (2000) [PubMed 11104663] for a review of the LTBP gene family.[supplied by OMIM]
• Uniprot ID: Q8N2S1
• Protein Accession #: NP_001036009.1
• Molecular Weight: 173 kDa