LRFN1 Antibody (OAPB00845)

Catalog No: OAPB00845

Size:100UG

Western blot analysis of LRFN1 in human brain lysate with LRFN1 antibody at (A) 1 and (B) 2 ug/mL.

Immunohistochemistry of LRFN1 in mouse brain tissue with LRFN1 antibody at 2.5 ug/mL.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. LRFN1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: LRFN1 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: LRFN1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LRFN1. The immunogen is located within amino acids 700 - 750 of LRFN1.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-LRFN1 antibody is Catalog # OEPB02962
• Application Info: LRFN1 antibody can be used for detection of LRFN1 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
• Reference: Morimura N, Inoue T, Katayama K, et al. Comparative analysis of structure, expression and PSD95-binding capacity of Lrfn, a novel family of neuronal transmembrane proteins. Gene2006; 380:72-83.;Kobe B and Kajava AV. The leucine-rich repeat as a protein recognition motif. Curr. Opin. Struct. Biol.2001; 11:725-32.;Aruga J and Mikoshiba K. Identification and characterization of Slitrk, a novel transmembrane protein family controlling neurite outgrowth. Mol. Cell Neurosci.2003; 24:117-29.;

Target Info

• Gene Symbol: LRFN1
• Gene Full Name: leucine rich repeat and fibronectin type III domain containing 1
• Alias Symbols: CTC-246B18.8;leucine-rich repeat and fibronectin type III domain-containing protein 1;SALM2;synaptic adhesion-like molecule 2.
• NCBI Gene Id: 57622
• Protein Name: Leucine-rich repeat and fibronectin type III domain-containing protein 1
• Description of Target: Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1 (By similarity).
• Uniprot ID: Q9P244