IRF4 Recombinant Protein (OPCD04533)

Catalog No: OPCD04533

IRF4 Recombinant Protein (OPCD04533) using SDS-PAGE

IRF4 Recombinant Protein (OPCD04533) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Asp175-His433
  Subcellular Location: Nucleus
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Irf4
• Gene Full Name: interferon regulatory factor 4
• Alias Symbols: AI385587;interferon regulatory factor 4;IRF;IRF-4;LSIRF;lymphocyte-specific interferon regulatory factor;NF-EM5;PU.1 interaction partner;Sfpi1/PU.1 interaction partner;Spip;transcriptional activator PIP.
• NCBI Gene Id: 16364
• Protein Name: Interferon regulatory factor 4
• Description of Target: Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.
• Uniprot ID: Q64287
• Protein Accession #: NP_038702.1
• Nucleotide Accession #: NM_013674.1
• Protein Size (# AA): Asp175~His433
• Molecular Weight: 33kDa