IPR1 Antibody (OAPB00607)

Catalog No: OAPB00607

Size:100UG

Western blot analysis of IPR1 in Hela cell lysate with IPR1 antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL.

Immunohistochemical staining of human brain tissue using IPR1 antibody at 2.5 ug/mL.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. IPR1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: IPR1 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: IPR1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human IPR1. The immunogen is located within amino acids 470 - 520 of IPR1.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-IPR1 antibody is Catalog # OEPB02726
• Application Info: Ipr1 antibody can be used for detection of Ipr1 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
• Reference: Pan H, Yan BS, Rojas M, et al. Ipr1 gene mediates innate immunity to tuberculosis. Nature2005; 434:767-72.;Bloch DB, Nakajima A, Gulick T, et al. Sp110 localizes to the PML-Sp100 nuclear body and may function as a nuclear hormone receptor transcriptional coactivator. Mol. Cell Biol.2000; 20:6138-46.; De la Fuente J, Manzano-Roman R, Blouin EF, et al. Sp110 transcription is induced and required by Anaplasma phagocytophilum for infection of human promyelocytic cells. BMC Infect. Dis.2007; 7:110.;Tosh K. Campbell SJ, Fielding K, et al. Variants in the SP110 gene are associated with genetic susceptibility to tuberculosis in West Africa. Proc. Natl. Acad. Sci.2006; 103:10364-8.

Target Info

• Gene Symbol: SP110
• Gene Full Name: SP110 nuclear body protein
• Alias Symbols: IFI41;IFI75;interferon-induced protein 41, 30kD;interferon-induced protein 41/75;interferon-induced protein 75, 52kD;IPR1;phosphoprotein 41;phosphoprotein 75;sp110 nuclear body protein;speckled 110 kDa;transcriptional coactivator Sp110;VODI.
• NCBI Gene Id: 3431
• Protein Name: Sp110 nuclear body protein|sp110 nuclear body protein isoform b [Homo sapiens]
• Description of Target: Transcription factor. May be a nuclear hormone receptor coactivator. Enhances transcription of genes with retinoic acid response elements (RARE).
• Uniprot ID: Q9HB58
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_004501