INHBB Antibody - N-terminal region (ARP81148_P050)

Catalog No: ARP81148_P050

Host: Rabbit
Target Name: INHBB
Sample Tissue: Human Neurofibroma Tumor lysates
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human INHBB
• Purification: Affinity purified
• Peptide Sequence: Synthetic peptide located within the following region: CLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGGFR
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-INHBB (ARP81148_P050) antibody is Catalog # AAP81148

Target Info

• Gene Symbol: INHBB
• Gene Full Name: inhibin beta B
• NCBI Gene Id: 3625
• Protein Name: inhibin beta B chain
• Description of Target: The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
• Uniprot ID: P09529
• Protein Accession #: NP_002184.2
• Nucleotide Accession #: NM_002193.2
• Protein Size (# AA): 407
• Molecular Weight: 44 kDa