IMMP2L Antibody - C-terminal region (ARP60563_P050)

Catalog No: ARP60563_P050

WB Suggested Anti-IMMP2L Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Lung

Host: Rabbit
Target Name: IMMP2L
Sample Tissue: Human 786-0 Whole Cell
Antibody Dilution: 3ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Cow, Guinea Pig, Horse
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IMMP2L
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 79%; Guinea Pig: 85%; Horse: 86%; Human: 100%
• Peptide Sequence: Synthetic peptide located within the following region: GHSFDSNSFGPVSLGLLHAHATHILWPPERWQKLESVLPPERLPVQREEE
• Concentration: 0.5 mg/ml
• Blocking Peptide: Catalog # AAP60563 (Previous Catalog # AAPP46613)
• Subunit: 2
• Publications:

  Role of Mitochondrial Glycerol-3-Phosphate Dehydrogenase in Metabolic Adaptations of Prostate Cancer. Cells. 9, NULL (2020). 32717855

  Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death. Cell Res. 28, 625-643 (2018). 29808012

• Description:
  View product citations for IMMP2L Antibody - C-terminal region (ARP60563_P050) on CiteAb

Target Info

• Gene Symbol: IMMP2L
• Gene Full Name: IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
• Alias Symbols: IMP2, IMP2-LIKE, IMMP2L-IT1
• NCBI Gene Id: 83943
• Protein Name: Mitochondrial inner membrane protease subunit 2
• Description of Target: The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMP1 (IMMP1L; MIM 612323) and IMP2 are the catalytic subunits of the IMP complex.
• Uniprot ID: Q96T52
• Protein Accession #: NP_115938
• Nucleotide Accession #: NM_032549
• Protein Size (# AA): 175
• Molecular Weight: 20kDa
• Protein Interactions: HNRNPD;