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| Datasheets/Manuals | Printable datasheet for IL-1ra Antibody - Biotin Conjugated (OASA11646) |
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| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Lyophilized. Phosphate buffered saline |
| Clonality | Polyclonal |
| Isotype | Polyclonal IgG |
| Host | Rabbit |
| Conjugation | Biotin |
| Application | Enzyme-linked immunosorbent assay|Western blot |
| Additional Information | Antiserum Preparation: Antiserum to human IL-1RA were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. |
| :: | Buffer Solutions: Phosphate buffered saline |
| Reconstitution and Storage | -20°C |
| Immunogen | Recombinant human IL-1RA (PHP080) |
| Predicted Homology Based on Immunogen Sequence | Human |
| Concentration | 0.1 mg/ml |
| Specificity | This product specifically recognises human Interleukin-1 receptor antagonist (IL-1RA), a naturally occurring inflammatory inhibitor protein, produced by monocytes, macrophages, neutrophils, corneal epithelial cells and fibroblasts, which inhibits the activity of IL-1 alpha and IL-1 beta, by competitively blocking binding to cell surface receptors for IL-1. Genetic variations in IL-1RA gene (IL1RN) are associated with susceptibility to microvascular complications of diabetes type 4 (MVCD4), and IL-1RA has therapeutic applications in rheumatoid arthritis, asthma, psoriasis, sepsis, chronic myelogenous leukaemia and inflammatory bowel disease. |
| Application Info | ELISA: Suggested dilution- 0.25-1.0 ug/ml; This biotinylated human IL-1RA antibody may be used in a direct ELISA or as the detection reagent in a sandwich ELISA with a purified human IL-1RA antibody (Catalog No. OASA11645) as the capture reagent and recombinant human IL-1RA (Catalog No. OPSA10975) as the standard. Western Blot: Suggested dilution- 0.1-0.2 ug/ml; This biotinylated human IL-1RA antibody may be used in Western Blotting applications under either reducing or non-reducing conditions with recombinant human IL-1RA (Catalog No. OPSA10975) as the positive control. |
| Alias Symbols | DIRA, IRAP, IL1F3, IL1RA, MVCD4, IL-1RN, IL-1ra, IL-1ra3, ICIL-1RA |
|---|---|
| NCBI Gene Id | 3557 |
| Protein Name | Interleukin-1 receptor antagonist protein |
| Description of Target | Rabbit Anti Human Interleukin-1RA:Biotin |
| Uniprot ID | P18510 |
| Protein Accession # | NP_000568.1 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "IL-1ra Antibody - Biotin Conjugated (OASA11646)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "IL-1ra Antibody - Biotin Conjugated (OASA11646)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "IL-1ra Antibody - Biotin Conjugated (OASA11646)" provided in?
This item is provided in "Lyophilized. Phosphate buffered saline".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "IL-1ra Antibody - Biotin Conjugated (OASA11646)"?
This target may also be called "DIRA, IRAP, IL1F3, IL1RA, MVCD4, IL-1RN, IL-1ra, IL-1ra3, ICIL-1RA" in publications.
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What is the shipping cost for "IL-1ra Antibody - Biotin Conjugated (OASA11646)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "IL-1ra Antibody - Biotin Conjugated (OASA11646)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "IL-1ra Antibody - Biotin Conjugated (OASA11646)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "IL-1ra Antibody - Biotin Conjugated (OASA11646)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for ""?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for ""?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with ""?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with ""?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with ""?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with ""?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.