ICK Recombinant Protein (OPCD04085)

Catalog No: OPCD04085

ICK Recombinant Protein (OPCD04085) using SDS-PAGE

ICK Recombinant Protein (OPCD04085) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Met1-Phe284
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 90%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Cilk1
• Gene Full Name: ciliogenesis associated kinase 1
• Alias Symbols: 2210420N10Rik;AI848300;Ic;Ick;intestinal cell kinase;MAK-related kinase;mICK;Mrk;serine/threonine-protein kinase ICK.
• NCBI Gene Id: 56542
• Protein Name: Serine/threonine-protein kinase ICK
• Description of Target: Has an essential role in ciliogenesis, particularly in neuronal and retinal progenitor cells (PubMed:24797473). Phosphorylates KIF3A (PubMed:24797473). Involved in the control of ciliary length (PubMed:24853502). Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (PubMed:24797473, PubMed:24853502). May play a role in cardiac development (By similarity). Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling -dependent manner and this regulation requires its kinase activity (PubMed:25243405).
• Uniprot ID: Q9JKV2
• Protein Accession #: NP_001157252.1
• Nucleotide Accession #: NM_001163780.1
• Protein Size (# AA): Met1~Phe284
• Molecular Weight: 34kDa