Human VEGF165 Protein (OPBI00002)

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SDS-PAGE analysis of human vascular endothelial growth factor 165 (VEGF165) is expressed by E. coli.

Technical Documents

Datasheets/Manuals	Printable datasheet for OPBI00002

Product Info

Product Info
Isotype	E.coli
Conjugation	Unconjugated
Application	SDS-PAGE
Reconstitution and Storage	Store at 4C for short term and -20C for long term storage
Immunogen	0.14mol/L NaCl, 0.027mol/L KCl, 0.01mol/L Na2PO4, 0.018mol/L KH2PO4
Concentration	100 ug (in 100 ul): 1 mg/ml. 500 ug (in 0.5 ul): 1 mg/ml
Purity	>85% as determined by SDS-PAGE

Target Info

Gene Symbol	Human VEGF165
Alias Symbols	VPF, VEGF, MVCD1
NCBI Gene Id	7422
Description of Target	Vascular endothelial growth factor (VEGF) is a signal protein that stimulates vasculogenesis and angiogenesis. VEGF-A can stimulate endothelial cell mitogenesis and cell migration. VEGF-A has many isoforms, of which VEGF165 is one of the most important
Uniprot ID	P15692
Protein Accession #	NP_003367.4
Nucleotide Accession #	NM_003376.5

Protocols & Data

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Protein interactions

Name	# of Products
ADAMTS1	36
AKT1	428
CSDA	43
CTGF	62
EPHB2	83
FLT1	46
GPC1	18
HIF1A	194
HSP90AA1	525	HSPA4	423
IGFBP7	103
KDR	121
NRP1	94
NRP2	36
PGF	32
RB1	474
SEMA3F	20
SPARC	118
TNXB	16
VEGFA	83
VEGFB	29
VTN	147
YBX1	193

Biological pathways

Name	# of Products
Activation of protein kinase activity	60
Basophil chemotaxis	13
Cell migration involved in sprouting angiogenesis	61
Cellular response to hypoxia	99
Endothelial cell chemotaxis	39
Induction of positive chemotaxis	49
Macrophage differentiation	51
Monocyte differentiation	32
Platelet activation	875
Platelet degranulation	443
Platelet-derived growth factor receptor signaling pathway	19
Positive regulation of angiogenesis	241
Positive regulation of blood vessel endothelial cell migration	76
Positive regulation of cell adhesion	73
Positive regulation of cell division	223
Positive regulation of CREB transcription factor activity	26
Positive regulation of endothelial cell proliferation	175
Positive regulation of leukocyte migration	24
Positive regulation of MAP kinase activity	147
Positive regulation of mast cell chemotaxis	22
Positive regulation of peptidyl-serine phosphorylation	168
Positive regulation of peptidyl-tyrosine phosphorylation	308
Positive regulation of protein autophosphorylation	71
Positive regulation of protein kinase C signaling cascade	17
Positive regulation of transcription from RNA polymerase II promoter	1210
Positive regulation of vascular endothelial growth factor receptor signaling pathway	88
Positive regulation of vascular permeability	31
Regulation of cell shape	126
Vascular endothelial growth factor receptor signaling pathway	45
Vasculogenesis	81

Biological process

Name	# of Products
Activation of protein kinase activity	27
Angiogenesis	196
Anti-apoptosis	239
Artery morphogenesis	29
Basophil chemotaxis	4
Behavior	47
Blood coagulation	396
Blood vessel remodeling	44
Camera-type eye morphogenesis	18
Cardiac muscle fiber development	6
Cell maturation	40
Cell migration involved in sprouting angiogenesis	20
Cellular response to hypoxia	44
Cellular response to vascular endothelial growth factor stimulus	16
Endothelial cell chemotaxis	9
Epithelial cell differentiation	53
Eye photoreceptor cell development	15
Growth	34
Heart morphogenesis	47
In utero embryonic development	199
Induction of positive chemotaxis	21
Kidney development	92
Lactation	44
Lung alveolus development	47
Macrophage differentiation	14
Mammary gland alveolus development	28
Mesoderm development	34
Monocyte differentiation	13
MRNA stabilization	15
Multicellular organismal development	896
Negative regulation of apoptotic process	356
Negative regulation of bone resorption	12
Nervous system development	384
Ovarian follicle development	60
Patterning of blood vessels	44
Platelet activation	202
Platelet degranulation	78
Platelet-derived growth factor receptor signaling pathway	27
Positive chemotaxis	33
Positive regulation of angiogenesis	97
Positive regulation of blood vessel endothelial cell migration	24
Positive regulation of branching involved in ureteric bud morphogenesis	26
Positive regulation of cell adhesion	48
Positive regulation of cell division	67
Positive regulation of cell migration	150
Positive regulation of cell migration involved in sprouting angiogenesis	8
Positive regulation of cell proliferation	483
Positive regulation of cellular component movement	17
Positive regulation of CREB transcription factor activity	14
Positive regulation of endothelial cell migration	36
Positive regulation of endothelial cell proliferation	68
Positive regulation of intracellular protein kinase cascade	13
Positive regulation of leukocyte migration	15
Positive regulation of MAP kinase activity	56
Positive regulation of mast cell chemotaxis	10
Positive regulation of mesenchymal cell proliferation	47
Positive regulation of peptidyl-serine phosphorylation	63
Positive regulation of peptidyl-tyrosine phosphorylation	112
Positive regulation of positive chemotaxis	13
Positive regulation of protein autophosphorylation	18
Positive regulation of protein kinase C signaling cascade	8
Positive regulation of smooth muscle cell proliferation	67
Positive regulation of transcription from RNA polymerase II promoter	968
Positive regulation of vascular endothelial growth factor receptor signaling pathway	20
Positive regulation of vascular permeability	16
Post-embryonic camera-type eye development	8
Primitive erythrocyte differentiation	6
Regulation of cell shape	99
Response to cold	31
Response to hypoxia	205
Signal transduction	1058
Surfactant homeostasis	15
T-helper 1 type immune response	14
Vascular endothelial growth factor receptor signaling pathway	42
Vasculogenesis	60

Cellular components

Name	# of Products
Basement membrane	61
Cell surface	369
Cytoplasm	4549
Extracellular region	1573
Extracellular space	884
Membrane	2769
Membrane-bounded vesicle	14
Platelet alpha granule lumen	42
Proteinaceous extracellular matrix	159
Secretory granule	77

Protein function

Name	# of Products
Cell surface binding	163
Chemoattractant activity	120
Cytokine activity	1104
Extracellular matrix binding	91
Fibronectin binding	119
Growth factor activity	831
Heparin binding	539
Platelet-derived growth factor receptor binding	96
Protein binding	12191
Protein heterodimerization activity	1132
Protein homodimerization activity	1852
Receptor agonist activity	52
Vascular endothelial growth factor receptor 1 binding	28
Vascular endothelial growth factor receptor 2 binding	60
Vascular endothelial growth factor receptor binding	26

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Human VEGF165 Protein (OPBI00002)

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