HTR2B Antibody - N-terminal region (OASG06798)

Catalog No: OASG06798

Size:100 uL

Western Blot using HT29

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IF
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the N-terminal region of human SR-2B. Location: 30-110aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: SR-2B Polyclonal Antibody detects endogenous levels of SR-2B protein.
• Application Info: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000;

Target Info

• Gene Symbol: HTR2B
• Gene Full Name: 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
• Alias Symbols: 5-HT2B, 5-HT-2B, 5-HT(2B)
• NCBI Gene Id: 3357;
• Description of Target: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved.
• Uniprot ID: P41595
• Molecular Weight: 54 kDa