HSP90AA1 Antibody (OAPA00259)

Catalog No: OAPA00259 (Formerly GWB-DL6631)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
• Clonality: Monoclonal
• Clone: P4F10AT.
• Isotype: Mouse IgG2b heavy chain and kappa light chain.
• Host: Mouse
• Application: WB, IHC
  Product Type: Mouse Anti Human Monoclonal.
  Product Introduction: HSP90 has been identified in the cytosol, nucleus and endoplasmic reticulum, and is reported to exist in many tissue types. In several tissues, including smooth muscle, HSP90 comprises up to 2% of total cellular protein. HSP90 functions as a dimer, assembled as part of heterocomplex. It possesses ATP-binding site and low ATPase activity. HSP90 is able to associate with actin filaments in certain conditions. Another important property of HSP90 is the binding of unoccupied steroid hormone receptors. HSP90 has been characterized as a molecular chaperone able to keep the target protein in a folding-competent state. It has an enhanced chaperone activity in oligomeric form at high temperatures. HSP90 function is sensitive to bivalent cations concentration.
• Reconstitution and Storage: For periods up to 1 month store at 4C, for longer periods of time, store at -20C. Prevent freeze thaw cycles.
  Stability: 12 months at -20C. 1 month at 4C.
• Immunogen: The immunogen for anti-HSP90 Alpaha antibody: anti-human HSP90A mAb, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HSP90A amino acids 1-732 purified from E. coli.
• Purity: HSP90A antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
• Application Info: HSP90A antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:500 ~ 1:2,000 and immunohistochemistry analysis is 1:100~200. Recommended starting dilution for Western blot is 1:1,000 and Immunohistochemistry is 1:100.

Target Info

• Gene Symbol: HSP90AA1
• Gene Full Name: Heat shock protein HSP 90-alpha
• Alias Symbols: EL52, HSPN, LAP2, HSP86, HSPC1, HSPCA, Hsp89, Hsp90, LAP-2, HSP89A, HSP90A, HSP90N, Hsp103, HSPCAL1, HSPCAL4, HEL-S-65p
• NCBI Gene Id: 3320
• Protein Name: Heat shock protein HSP 90-alpha
• Description of Target: Mouse Anti Human Heat shock protein HSP 90-alpha
• Uniprot ID: P07900
• Protein Accession #: NP_001017963.2; NP_005339.3
• Nucleotide Accession #: NM_001017963.2; NM_005348.3